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NCT05723679 · ClinicalTrials.gov registry record · NA
Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF
A NA study of Obesity and Heart Failure With Preserved Ejection Fraction, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 78
- Enrollment target
- 1
- Study location
NCT05723679: Recruiting NA study of Obesity and Heart Failure With Preserved Ejection Fraction, sponsored by University of Texas Southwestern Medical Center.
NCT05723679 is a NA study of Obesity and Heart Failure With Preserved Ejection Fraction that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 78 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05723679, a NA study of Obesity and Heart Failure With Preserved Ejection Fraction, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 78 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall purpose of this study is to investigate whether pulmonary limitations that increase the oxygen (O2) cost of breathing impact dyspnea on exertion (DOE) and peak exercise capacity in patients with HFpEF and obesity. As per investigator's hypothesis, obesity is likely a significant contributor to DOE and exercise intolerance in patients with HFpEF.
Primary Outcome
O2 cost of breathing measured during eucapnic voluntary hyperventilation, and calculated using oxygen uptake and ventilation variables.
Conditions Studied
Interventions
- OTHER HeO2 gas mixture
- OTHER Room air gas mixture
Study Locations (1)
Texas
- UT Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 78 participants |
| Start Date | 2023-07-01 |
| Est. Completion | 2029-06-30 |
| Phase | NA |
What NCT05723679 shows while recruiting
NCT05723679 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 78 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which HeO2 gas mixture is the first listed.
NCT05723679 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05723679 about?
NCT05723679 is a clinical study titled "Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF". The overall purpose of this study is to investigate whether pulmonary limitations that increase the oxygen (O2) cost of breathing impact dyspnea on exertion (DOE) and peak exercise capacity in patients with HFpEF and obesity. As per investigator's hypothesis, obesity is likely a significant contribu...
What is the current status of trial NCT05723679?
This trial is currently recruiting. It is a NA study. The enrollment target is 78 participants. The study started on 2023-07-01. Estimated completion is 2029-06-30.
What conditions does trial NCT05723679 study?
This clinical trial studies the following conditions: Obesity, Heart Failure With Preserved Ejection Fraction.
What interventions are being tested in trial NCT05723679?
The interventions under investigation include: HeO2 gas mixture (OTHER), Room air gas mixture (OTHER).
Who is sponsoring clinical trial NCT05723679?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05723679 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05723679's enrollment target sits among peer trials
78 561st of 1053 higher than 491 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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