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NCT05839535 · ClinicalTrials.gov registry record · Phase 2
Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA
A Phase 2 study of Knee Osteoarthritis, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 140
- Enrollment target
- 1
- Study location
NCT05839535: Recruiting Phase 2 study of Knee Osteoarthritis, sponsored by Massachusetts General Hospital.
NCT05839535 is a Phase 2 study of Knee Osteoarthritis that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 140 participants, below the 303-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (54% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05839535, a Phase 2 study of Knee Osteoarthritis, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 140 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will combine brain imaging and neuromodulation tools to investigate the underlying neurobiological mechanisms of exercises. The findings will enhance our understanding of the mechanisms underlying mind-body exercise and facilitate the development of new pain management approaches.
Primary Outcome
Changes in brain resting-state connectivity between the primary motor cortex (M1) and other brain regions pre- and post-treatments, analyzed using the CONN Toolbox (https://web.conn-toolbox.org/)
Conditions Studied
Interventions
- DEVICE sham tDCS
- DEVICE tDCS
- BEHAVIORAL BDJ
- OTHER exercise
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Charlestown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2024-03-05 |
| Est. Completion | 2028-08-31 |
| Phase | Phase 2 |
What NCT05839535 shows while recruiting
NCT05839535 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 303-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (54% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 4 interventions - of which sham tDCS is the first listed.
NCT05839535 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05839535 about?
NCT05839535 is a clinical study titled "Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA". This study will combine brain imaging and neuromodulation tools to investigate the underlying neurobiological mechanisms of exercises. The findings will enhance our understanding of the mechanisms underlying mind-body exercise and facilitate the development of new pain management approaches.
What is the current status of trial NCT05839535?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 140 participants. The study started on 2024-03-05. Estimated completion is 2028-08-31.
What conditions does trial NCT05839535 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT05839535?
The interventions under investigation include: sham tDCS (DEVICE), tDCS (DEVICE), BDJ (BEHAVIORAL), exercise (OTHER).
Who is sponsoring clinical trial NCT05839535?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05839535 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05839535's enrollment target sits among peer trials
140 36th of 101 higher than 66 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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