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NCT05025787 · ClinicalTrials.gov registry record · Phase 2
A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
A Phase 2 study of Knee Osteoarthritis, sponsored by Maurizio Fava, MD.
- Completed
- Registry status
- Phase 2
- Development phase
- 55
- Enrollment target
- 16
- Study locations
NCT05025787: Completed Phase 2 study of Knee Osteoarthritis, sponsored by Maurizio Fava, MD.
NCT05025787 is a Phase 2 study of Knee Osteoarthritis that has completed, run by Maurizio Fava, MD. The registered enrollment target is 55 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (82% lower). The trial reports 16 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05025787, a Phase 2 study of Knee Osteoarthritis, has completed, sponsored by Maurizio Fava, MD.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 55 participants
- Enrollment target
- 16
- Study locations
Study Summary
The primary objective of this study is to evaluate the safety and efficacy of CNTX-6970 for the treatment of pain related to OA of the knee compared to placebo. CNTX-6970 is being developed as a new treatment for chronic pain, including painful osteoarthritis of the knee.
Primary Outcome
The primary outcome measure used to assess efficacy will be patient-reported knee pain using the WOMAC Part A (Bellamy, et al., 1988).We will use the numerical rating scale version of the WOMAC, with the subject assessing each of 5 questions using an 11-point (0 to 10) scale; the total score is the sum of the individual item scores (range 0-50). A higher WOMAC score represents worse symptom severity.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG CNTX-6970
Study Locations (16)
New York
- New York University Langone Health - New York
- Icahn School of Medicine at Mount Sinai - New York
- University of Rochester - Rochester
- Montefiore Medical Center - The Bronx
California
- University of California San Diego - La Jolla
- University of California- Davis - Sacramento
Florida
- University of Florida - Gainesville
- M&M Clinical Trials - Miami
Pennsylvania
- University of Pennsylvania - Philadelphia
- University of Pittsburgh - Pittsburgh
Massachusetts
- Massachusetts General Hospital - Boston
Missouri
- Healthcare Research Network - Hazelwood
North Carolina
- Center for Clinical Research - Winston-Salem
Texas
- UTsouthwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2021-10-25 |
| Est. Completion | 2024-06-11 |
| Phase | Phase 2 |
What the finished NCT05025787 record still lists
NCT05025787 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05025787 lists 16 locations in 10 states (New York, California, Florida).
Frequently Asked Questions
What is clinical trial NCT05025787 about?
NCT05025787 is a clinical study titled "A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.". The primary objective of this study is to evaluate the safety and efficacy of CNTX-6970 for the treatment of pain related to OA of the knee compared to placebo. CNTX-6970 is being developed as a new treatment for chronic pain, including painful osteoarthritis of the knee.
What is the current status of trial NCT05025787?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 2021-10-25. Estimated completion is 2024-06-11.
What conditions does trial NCT05025787 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT05025787?
The interventions under investigation include: Placebo (DRUG), CNTX-6970 (DRUG).
Who is sponsoring clinical trial NCT05025787?
This trial is sponsored by Maurizio Fava, MD, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05025787 being conducted?
This trial has 16 study locations across California, Florida, Massachusetts, Missouri, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05025787's enrollment target sits among peer trials
55 66th of 101 higher than 36 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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