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NCT05819892 · ClinicalTrials.gov registry record · Phase 1

Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer

A Phase 1 study of Endometrial Cancer, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
21
Enrollment target
1
Study location

NCT05819892: Recruiting Phase 1 study of Endometrial Cancer, sponsored by M.D. Anderson Cancer Center.

NCT05819892 is a Phase 1 study of Endometrial Cancer that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 21 participants, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05819892, a Phase 1 study of Endometrial Cancer, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
21 participants
Enrollment target
1
Study location

Study Summary

To learn if chemotherapy given in combination with radiation therapy, followed by maintenance therapy, can help to control endometrial cancer. The safety and effects of this study treatment will also be studied

Conditions Studied

Interventions

  • DRUG Carboplatin
  • DRUG Cisplatin
  • DRUG Paclitaxel
  • DRUG Dostarlimab

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2023-07-17
Est. Completion 2028-03-01
Phase Phase 1
M.D. Anderson Cancer Center

2,692 total trials

What NCT05819892 shows while recruiting

NCT05819892 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (96% lower).

The record links to 1 condition, with Endometrial Cancer appearing as the primary indexed condition, and to 4 interventions - of which Carboplatin is the first listed.

NCT05819892 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05819892 about?

NCT05819892 is a clinical study titled "Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer". To learn if chemotherapy given in combination with radiation therapy, followed by maintenance therapy, can help to control endometrial cancer. The safety and effects of this study treatment will also be studied

What is the current status of trial NCT05819892?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2023-07-17. Estimated completion is 2028-03-01.

What conditions does trial NCT05819892 study?

This clinical trial studies the following conditions: Endometrial Cancer.

What interventions are being tested in trial NCT05819892?

The interventions under investigation include: Carboplatin (DRUG), Cisplatin (DRUG), Paclitaxel (DRUG), Dostarlimab (DRUG).

Who is sponsoring clinical trial NCT05819892?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05819892 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Endometrial Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05819892's enrollment target sits among peer trials

21 166th of 181 higher than 12 of 181 other Endometrial Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Endometrial Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05819892, the US trial registry maintained by the National Library of Medicine. NCT05819892 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.