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NCT05801809 · ClinicalTrials.gov registry record · NA
Understanding the Effects of Transauricular Vagus Nerve Stimulation on Neural Networks and Autonomic Nervous System
A NA study of Healthy Volunteers, sponsored by Spaulding Rehabilitation Hospital.
- Active
- Registry status
- NA
- Development phase
- 44
- Enrollment target
- 1
- Study location
NCT05801809: Active NA study of Healthy Volunteers, sponsored by Spaulding Rehabilitation Hospital.
NCT05801809 is a NA study of Healthy Volunteers that is active but no longer recruiting, run by Spaulding Rehabilitation Hospital. The registered enrollment target is 44 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05801809, a NA study of Healthy Volunteers, is active but no longer recruiting, sponsored by Spaulding Rehabilitation Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 44 participants
- Enrollment target
- 1
- Study location
Study Summary
This trial aims to perform an exploratory, mechanistic, randomized double-blind sham-control trial in healthy participants to assess the physiologic effects of a single 60 minutes session of bilateral taVNS, on neural networks and autonomic function.
Primary Outcome
Resting-state EEG was recorded using a 64-channel high-density EGI system (Electrical Geodesics, Inc., Eugene, USA) under the eyes closed condition. Data was filtered into standard frequency bands using short-time Fourier transformation (STFT): delta (0.5-4 Hz), theta (4-8 Hz), alpha (8-13 Hz), beta (13-30 Hz), and gamma (30-80 Hz). Frontal asymmetry was computed as the difference in power between homologous left and right frontal electrodes (e.g., F3-F4) in the alpha band.
Conditions Studied
Interventions
- DEVICE Transauricular vagus nerve stimulation (taVNS)
Study Locations (1)
Massachusetts
- Spaulding Hospital Cambridge - Cambridge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2023-04-26 |
| Est. Completion | 2026-03-01 |
| Phase | NA |
What the registry record for NCT05801809 still lists
NCT05801809 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 1 intervention - of which Transauricular vagus nerve stimulation (taVNS) is the first listed.
NCT05801809 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05801809 about?
NCT05801809 is a clinical study titled "Understanding the Effects of Transauricular Vagus Nerve Stimulation on Neural Networks and Autonomic Nervous System". This trial aims to perform an exploratory, mechanistic, randomized double-blind sham-control trial in healthy participants to assess the physiologic effects of a single 60 minutes session of bilateral taVNS, on neural networks and autonomic function.
What is the current status of trial NCT05801809?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 44 participants. The study started on 2023-04-26. Estimated completion is 2026-03-01.
What conditions does trial NCT05801809 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT05801809?
The interventions under investigation include: Transauricular vagus nerve stimulation (taVNS) (DEVICE).
Who is sponsoring clinical trial NCT05801809?
This trial is sponsored by Spaulding Rehabilitation Hospital, which has 101 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05801809 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05801809's enrollment target sits among peer trials
44 148th of 283 higher than 135 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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