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NCT06552754 · ClinicalTrials.gov registry record · NA

Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

A NA study of Healthy Volunteers and Virtual Reality, sponsored by National Human Genome Research Institute (NHGRI).

Recruiting
Registry status
NA
Development phase
150
Enrollment target
2
Study locations

NCT06552754: Recruiting NA study of Healthy Volunteers and Virtual Reality, sponsored by National Human Genome Research Institute (NHGRI).

NCT06552754 is a NA study of Healthy Volunteers and Virtual Reality that is actively recruiting participants, run by National Human Genome Research Institute (NHGRI). The registered enrollment target is 150 participants, below the 481-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (69% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06552754, a NA study of Healthy Volunteers and Virtual Reality, is actively recruiting participants, sponsored by National Human Genome Research Institute (NHGRI).

RECRUITING
Registry status
NA
Development phase
150 participants
Enrollment target
2
Study locations

Study Summary

Background: People use virtual reality (VR) technology to play games, socialize, work, or receive medical care. Some people have "cybersickness" after using VR. Cybersickness is similar to motion sickness. Symptoms include eye strain, nausea, dizziness, or headache. The symptoms are usually mild and go away after the person stops using VR. New software called Motion Reset is being designed to reduce symptoms of cybersickness during VR use. Objective: To see if Motion Reset software can reduce cybersickness in people using VR. Eligibility: Healthy adults aged 18 to 60 years. Design: Participants will have 1 clinic visit that will last about 1 hour. They will answer questions about how they are feeling. They will learn how to use the VR headset and the handheld game controllers. The study will be broken into 2 parts. For the first part, participants will be assigned to 1 of 3 groups: Group 1 will participate in a VR experience designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller. Group 2 will participate in a VR experience that is not designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller. Group 3 will have no VR experience. Participants will complete 2 questionnaires about their experiences in the first part of the study. For the second part, all participants will spend up to 20 minutes playing a commercial VR game called Jurassic World Aftermath. Every few minutes, they will be asked if they are experiencing discomfort. After playing the game, participants will complete 12 questionnaires about their experience....

Primary Outcome

Assessed on numerical scale

Interventions

  • BEHAVIORAL Placebo
  • BEHAVIORAL Motion Reset

Study Locations (2)

Iowa

  • Iowa State University - Ames

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2025-09-26
Est. Completion 2026-07-01
Phase NA

What NCT06552754 shows while recruiting

NCT06552754 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 481-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (69% lower).

The record links to 2 conditions, with Healthy Volunteers appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06552754 reports a single indexed study location in Iowa, Maryland.

Frequently Asked Questions

What is clinical trial NCT06552754 about?

NCT06552754 is a clinical study titled "Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers". Background: People use virtual reality (VR) technology to play games, socialize, work, or receive medical care. Some people have "cybersickness" after using VR. Cybersickness is similar to motion sickness. Symptoms include eye strain, nausea, dizziness, or headache. The symptoms are usually mild an...

What is the current status of trial NCT06552754?

This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2025-09-26. Estimated completion is 2026-07-01.

What conditions does trial NCT06552754 study?

This clinical trial studies the following conditions: Healthy Volunteers, Virtual Reality.

What interventions are being tested in trial NCT06552754?

The interventions under investigation include: Placebo (BEHAVIORAL), Motion Reset (BEHAVIORAL).

Who is sponsoring clinical trial NCT06552754?

This trial is sponsored by National Human Genome Research Institute (NHGRI), which has 185 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06552754 being conducted?

This trial has 2 study locations across Iowa, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteers

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06552754's enrollment target sits among peer trials

150 57th of 283 higher than 225 of 283 other Healthy Volunteers trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06552754, the US trial registry maintained by the National Library of Medicine. NCT06552754 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.