Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05724810 · ClinicalTrials.gov registry record · NA
Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia
A NA study of Schizophrenia and Smoking Cessation, sponsored by Stony Brook University.
- Recruiting
- Registry status
- NA
- Development phase
- 38
- Enrollment target
- 1
- Study location
NCT05724810 is a NA study of Schizophrenia and Smoking Cessation that is actively recruiting participants, run by Stony Brook University. The registered enrollment target is 38 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05724810, a NA study of Schizophrenia and Smoking Cessation, is actively recruiting participants, sponsored by Stony Brook University.
- RECRUITING
- Registry status
- NA
- Development phase
- 38 participants
- Enrollment target
- 1
- Study location
Study Summary
Purpose of the study: Evaluate the effect of deep repetitive transcranial magnetic stimulation (deep rTMS; hereafter abbreviated as "dTMS") on synaptic density measured with positron emission tomography (PET) and the radiotracer \[11C\]UCB-J. The investigators also seek to link plasticity changes in the regions targeted by the electric field (especially, the insula) to changes in the functioning of insula circuits and behavioral cigarette usage in patients with schizophrenia (SCZ). Importance of the study: This is the first study designed to directly evaluate the mechanism of action (MOA) of dTMS for smoking disruption in patients with SCZ. Patients with SCZ are a vulnerable population in high, immediate need of new smoking therapeutics for reducing premature morbidity and mortality.
Conditions Studied
Interventions
- DEVICE Active deep transcranial magnetic stimulation (dTMS)
- DEVICE Sham dTMS
Study Locations (1)
New York
- Stony Brook University - Stony Brook
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2023-04-04 |
| Est. Completion | 2028-08-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05724810
The ClinicalTrials.gov registry entry for NCT05724810 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (83% lower). The listed sponsor is Stony Brook University, which has 127 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Active deep transcranial magnetic stimulation (dTMS) is the first listed.
NCT05724810 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT05724810 about?
NCT05724810 is a clinical study titled "Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia". Purpose of the study: Evaluate the effect of deep repetitive transcranial magnetic stimulation (deep rTMS; hereafter abbreviated as "dTMS") on synaptic density measured with positron emission tomography (PET) and the radiotracer \[11C\]UCB-J. The investigators also seek to link plasticity changes in...
What is the current status of trial NCT05724810?
This trial is currently recruiting. It is a NA study. The enrollment target is 38 participants. The study started on 2023-04-04. Estimated completion is 2028-08-31.
What conditions does trial NCT05724810 study?
This clinical trial studies the following conditions: Schizophrenia, Smoking Cessation, Tobacco Use.
What interventions are being tested in trial NCT05724810?
The interventions under investigation include: Active deep transcranial magnetic stimulation (dTMS) (DEVICE), Sham dTMS (DEVICE).
Who is sponsoring clinical trial NCT05724810?
This trial is sponsored by Stony Brook University, which has 127 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05724810 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Taking Action for College Students
RECRUITING · NA
-
Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
RECRUITING · NA
-
Getting Out of the House: Using Behavioral Activation to Increase Community Participation
RECRUITING · NA
-
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
RECRUITING · NA
-
Cerebellar Modulation of Cognition in Psychosis
RECRUITING · NA
-
TMS for Inhibition Enhancement in Schizophrenia
RECRUITING · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.