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NCT05695196 · ClinicalTrials.gov registry record · Phase 1
Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant
A Phase 1 study of Microbial Colonization and Staphylococcus Aureus, sponsored by Johns Hopkins University.
- Active
- Registry status
- Phase 1
- Development phase
- 34
- Enrollment target
- 1
- Study location
NCT05695196: Active Phase 1 study of Microbial Colonization and Staphylococcus Aureus, sponsored by Johns Hopkins University.
NCT05695196 is a Phase 1 study of Microbial Colonization and Staphylococcus Aureus that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 34 participants, below the 12,653-participant average among 20 other Microbial Colonization trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05695196, a Phase 1 study of Microbial Colonization and Staphylococcus Aureus, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 34 participants
- Enrollment target
- 1
- Study location
Study Summary
This feasibility and safety pilot study looks to determine whether transferring a parents healthy, diverse nasal microbiota to the participant's infant(s) will create a healthy, diverse neonatal nasal microbiome.
Primary Outcome
This outcome will be determined by analysis of periodic surveillance swabs collected after intervention.
Conditions Studied
Interventions
- BIOLOGICAL Placebo
- BIOLOGICAL nasal microbiota transplant (NMT)
Study Locations (1)
Maryland
- Johns Hopkins University - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2023-10-25 |
| Est. Completion | 2026-12-01 |
| Phase | Phase 1 |
What the registry record for NCT05695196 still lists
NCT05695196 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 12,653-participant average among 20 other Microbial Colonization trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Microbial Colonization appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05695196 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05695196 about?
NCT05695196 is a clinical study titled "Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant". This feasibility and safety pilot study looks to determine whether transferring a parents healthy, diverse nasal microbiota to the participant's infant(s) will create a healthy, diverse neonatal nasal microbiome.
What is the current status of trial NCT05695196?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 34 participants. The study started on 2023-10-25. Estimated completion is 2026-12-01.
What conditions does trial NCT05695196 study?
This clinical trial studies the following conditions: Microbial Colonization, Staphylococcus Aureus, Neonatal Infection.
What interventions are being tested in trial NCT05695196?
The interventions under investigation include: Placebo (BIOLOGICAL), nasal microbiota transplant (NMT) (BIOLOGICAL).
Who is sponsoring clinical trial NCT05695196?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05695196 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Microbial Colonization
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05695196's enrollment target sits among peer trials
34 15th of 20 higher than 6 of 20 other Microbial Colonization trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Microbial Colonization trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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