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NCT05688410 · ClinicalTrials.gov registry record · NA
Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)
A NA study of Pain and Opioid Use Disorder, sponsored by Case Western Reserve University.
- Active
- Registry status
- NA
- Development phase
- 198
- Enrollment target
- 2
- Study locations
NCT05688410: Active NA study of Pain and Opioid Use Disorder, sponsored by Case Western Reserve University.
NCT05688410 is a NA study of Pain and Opioid Use Disorder that is active but no longer recruiting, run by Case Western Reserve University. The registered enrollment target is 198 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (35% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05688410, a NA study of Pain and Opioid Use Disorder, is active but no longer recruiting, sponsored by Case Western Reserve University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 198 participants
- Enrollment target
- 2
- Study locations
Study Summary
This work will involve conducting a randomized trial that will evaluate preliminary efficacy of "assisted" rate cycling, voluntary rate cycling and psychotherapy for pain individually and in combination as adjunctive treatments on cravings (primary outcome) in adults with an opioid use disorder. The investigators will also evaluate the effects of "assisted" rate cycling, voluntary rate cycling and I-STOP on secondary outcomes including depression, anxiety and sleep.
Primary Outcome
Change in drug cravings: self-report, visual analog scale (VAS), higher scores indicate higher levels of cravings;
Conditions Studied
Interventions
- OTHER Exercise
- BEHAVIORAL Psychotherapy Pain and Addiction (I-STOP)
Study Locations (2)
Colorado
- University of Colorado at Denver - Denver
Ohio
- Case Western Reserve University - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 198 participants |
| Start Date | 2023-02-10 |
| Est. Completion | 2026-11-30 |
| Phase | NA |
What the registry record for NCT05688410 still lists
NCT05688410 is an interventional study that assigns participants to a tested intervention. The registered 198 participants enrollment target is mid-sized for trials with a published cap, below the 304-participant average among 374 other Pain trials with a reported enrollment target (35% lower).
The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 2 interventions - of which Exercise is the first listed.
NCT05688410 reports a single indexed study location in Colorado, Ohio.
Frequently Asked Questions
What is clinical trial NCT05688410 about?
NCT05688410 is a clinical study titled "Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)". This work will involve conducting a randomized trial that will evaluate preliminary efficacy of "assisted" rate cycling, voluntary rate cycling and psychotherapy for pain individually and in combination as adjunctive treatments on cravings (primary outcome) in adults with an opioid use disorder. The...
What is the current status of trial NCT05688410?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 198 participants. The study started on 2023-02-10. Estimated completion is 2026-11-30.
What conditions does trial NCT05688410 study?
This clinical trial studies the following conditions: Pain, Opioid Use Disorder.
What interventions are being tested in trial NCT05688410?
The interventions under investigation include: Exercise (OTHER), Psychotherapy Pain and Addiction (I-STOP) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05688410?
This trial is sponsored by Case Western Reserve University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05688410 being conducted?
This trial has 2 study locations across Colorado, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05688410's enrollment target sits among peer trials
198 89th of 374 higher than 284 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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