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Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
NCT06374238 · View on ClinicalTrials.gov ↗
Study Summary
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable population.
Conditions Studied
Interventions
- BEHAVIORAL Usual Care
- BEHAVIORAL CBT+ Health coach
- BEHAVIORAL CBT w/o Health Coach ( self-guided)
Study Locations (14)
New York
- Weil Cornell Medical College — New York
- University of Rochester Medical Center — Rochester
North Carolina
- Wake Forest Baptist Hospital — Durham
- East Carolina University Health Medical Center — Greenville
Pennsylvania
- UPMC University of Pittsburgh Classical Hematology Adult Clinic — Pittsburgh
- UPMC Children's Hospital of Pittsburgh — Pittsburgh
Alabama
- University of South Alabama Medical Center — Mobile
California
- UCLA Mattel Children's Hospital Ronald Reagan Hospital — Los Angeles
Connecticut
- Connecticut Children's Medical Center — Hartford
Georgia
- Children's Healthcare of Atlanta — Atlanta
Illinois
- Ann and Robert H. Lurie Children's Hospital of Chicago — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 470 participants |
| Start Date | 2025-03-10 |
| Est. Completion | 2028-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06374238
The ClinicalTrials.gov registry entry for NCT06374238 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 470 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,082 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 3 interventions — of which Usual Care is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06374238 reports 14 study locations spanning 11 distinct geographic areas — top geographies include New York, North Carolina, Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06374238 about?
NCT06374238 is a clinical study titled "Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain". The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also se...
What is the current status of trial NCT06374238?
This trial is currently recruiting. It is a NA study. The enrollment target is 470 participants. The study started on 2025-03-10. Estimated completion is 2028-05.
What conditions does trial NCT06374238 study?
This clinical trial studies the following conditions: Pain, Sickle Cell Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06374238?
The interventions under investigation include: Usual Care (BEHAVIORAL), CBT+ Health coach (BEHAVIORAL), CBT w/o Health Coach ( self-guided) (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06374238?
This trial is sponsored by University of Pittsburgh, which has 1,082 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06374238 being conducted?
This trial has 14 study locations across Alabama, California, Connecticut, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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