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NCT06374238 · ClinicalTrials.gov registry record · NA
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
A NA study of Pain and Sickle Cell Disease, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- NA
- Development phase
- 470
- Enrollment target
- 14
- Study locations
NCT06374238: Recruiting NA study of Pain and Sickle Cell Disease, sponsored by University of Pittsburgh.
NCT06374238 is a NA study of Pain and Sickle Cell Disease that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 470 participants, above the 303-participant average among 374 other Pain trials with a reported enrollment target (55% higher). The trial reports 14 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06374238, a NA study of Pain and Sickle Cell Disease, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- NA
- Development phase
- 470 participants
- Enrollment target
- 14
- Study locations
Study Summary
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable population.
Primary Outcome
Mean change in pain intensity as measured by the Pain, Enjoyment of Life and General Activity (PEG-3) scale. Item 1 asks individuals to rate their pain, on average, over the past week, using a 0-10 rating scale.
Conditions Studied
Interventions
- BEHAVIORAL Usual Care
- BEHAVIORAL CBT+ Health coach
- BEHAVIORAL CBT w/o Health Coach ( self-guided)
Study Locations (14)
New York
- Weil Cornell Medical College - New York
- University of Rochester Medical Center - Rochester
North Carolina
- Wake Forest Baptist Hospital - Durham
- East Carolina University Health Medical Center - Greenville
Pennsylvania
- UPMC University of Pittsburgh Classical Hematology Adult Clinic - Pittsburgh
- UPMC Children's Hospital of Pittsburgh - Pittsburgh
Alabama
- University of South Alabama Medical Center - Mobile
California
- UCLA Mattel Children's Hospital Ronald Reagan Hospital - Los Angeles
Connecticut
- Connecticut Children's Medical Center - Hartford
Georgia
- Children's Healthcare of Atlanta - Atlanta
Illinois
- Ann and Robert H. Lurie Children's Hospital of Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 470 participants |
| Start Date | 2025-03-10 |
| Est. Completion | 2028-05 |
| Phase | NA |
What NCT06374238 shows while recruiting
NCT06374238 is an interventional study that assigns participants to a tested intervention. The registered 470 participants enrollment target is mid-sized for trials with a published cap, above the 303-participant average among 374 other Pain trials with a reported enrollment target (55% higher).
The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 3 interventions - of which Usual Care is the first listed.
NCT06374238 lists 14 locations in 11 states (New York, North Carolina, Pennsylvania).
Frequently Asked Questions
What is clinical trial NCT06374238 about?
NCT06374238 is a clinical study titled "Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain". The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also se...
What is the current status of trial NCT06374238?
This trial is currently recruiting. It is a NA study. The enrollment target is 470 participants. The study started on 2025-03-10. Estimated completion is 2028-05.
What conditions does trial NCT06374238 study?
This clinical trial studies the following conditions: Pain, Sickle Cell Disease.
What interventions are being tested in trial NCT06374238?
The interventions under investigation include: Usual Care (BEHAVIORAL), CBT+ Health coach (BEHAVIORAL), CBT w/o Health Coach ( self-guided) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06374238?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06374238 being conducted?
This trial has 14 study locations across Alabama, California, Connecticut, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06374238's enrollment target sits among peer trials
470 37th of 374 higher than 338 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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