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NCT05636176 · ClinicalTrials.gov registry record · Phase 3
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
A Phase 3 study of Heart Failure, sponsored by Novo Nordisk A/S.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 5,600
- Enrollment target
- 20
- Study locations
NCT05636176 is a Phase 3 study of Heart Failure that is actively recruiting participants, run by Novo Nordisk A/S. The registered enrollment target is 5,600 participants, above the 2,035-participant average among 397 other Heart Failure trials with a reported enrollment target (175% higher). The trial reports 20 study locations across 4 states.
The verdict
NCT05636176, a Phase 3 study of Heart Failure, is actively recruiting participants, sponsored by Novo Nordisk A/S.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 5,600 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will either get ziltivekimab or placebo. Participants will get study medicine for once-monthly injections either in a pre-filled syringe to inject the study medicine into a skinfold or a pen-injector to inject the study medicine into flat skin. The study is expected to last for up to 4 years. Participants will have up to 20 clinic visits. Participants will have to use a study app on their phone to record and share information about all their injections of study medicine and to fill in questionnaires.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Ziltivekimab
Study Locations (20)
California
- InvivoCure -2 - Alhambra
- National Heart Institute Cal - Beverly Hills
- Valley Clinical Trials - Covina
- Scripps Memorial Hospital La Jolla - La Jolla
- Purushotham & Akther Kotha MD, inc. - La Mesa
- VA Loma Linda Hlthcr Sys - Loma Linda
- Biopharma Clinical Research Services, LLC - Los Angeles
- VA Greater Los Angeles Hlthcare System - Los Angeles
- VAGrtrLosAngelesHlthcareSystem - Los Angeles
- Valley Clinical Trials, Inc. - Northridge
- UCI Health - Orange
- Stanford Univ School of Med - Palo Alto
- San Diego Cardiac Center - San Diego
- North America Research Institute - San Dimas
Alabama
- Advanced Cardiovascular, LLC - Alexander City
- Eastern Shore Rsrch Inst, LLC - Fairhope
- Heart Center Rsrch_Hunstville - Huntsville
Arizona
- Banner University Medical Ctr - Phoenix
- Banner University Medical Ctr - Phoenix
Arkansas
- Cardiology & Medicine Clinic - Little Rock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5,600 participants |
| Start Date | 2023-05-08 |
| Est. Completion | 2027-07-02 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05636176
The ClinicalTrials.gov registry entry for NCT05636176 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 5,600 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 2,035-participant average among 397 other Heart Failure trials with a reported enrollment target (175% higher). The listed sponsor is Novo Nordisk A/S, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05636176 reports 20 study locations spanning 4 distinct geographic areas - top geographies include California, Alabama, Arizona.
Frequently Asked Questions
What is clinical trial NCT05636176 about?
NCT05636176 is a clinical study titled "A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation". This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will either get ziltivekimab or placebo. Participants will get study medicine for once-monthly injections either in a pre-filled syringe to inject the study medicine in...
What is the current status of trial NCT05636176?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 5,600 participants. The study started on 2023-05-08. Estimated completion is 2027-07-02.
What conditions does trial NCT05636176 study?
This clinical trial studies the following conditions: Heart Failure.
What interventions are being tested in trial NCT05636176?
The interventions under investigation include: Placebo (DRUG), Ziltivekimab (DRUG).
Who is sponsoring clinical trial NCT05636176?
This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05636176 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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