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NCT05523817 · ClinicalTrials.gov registry record · NA

Targeting Specific Brain Networks to Treat Specific Symptoms in Depression

A NA study of Major Depressive Disorder, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT05523817 is a NA study of Major Depressive Disorder that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 80 participants, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05523817, a NA study of Major Depressive Disorder, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

Repetitive transcranial magnetic stimulation (rTMS) is a way of non-invasively stimulating specific brain networks and is an established treatment for Major Depressive Disorder (MDD). This proposal will reveal network mechanisms of the therapeutic effects of rTMS by investigating how stimulating each network specifically changes network connectivity and behavior. This will be done in a highly individualized manner in depressed and healthy patients, leading to more effective and more individualized treatments for depression.

Conditions Studied

Interventions

  • DEVICE Intermittent Theta Burst Stimulation (iTBS)

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2024-03-12
Est. Completion 2028-12-31
Phase NA

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT05523817

The ClinicalTrials.gov registry entry for NCT05523817 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (79% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Major Depressive Disorder appearing as the primary indexed condition, and to 1 intervention - of which Intermittent Theta Burst Stimulation (iTBS) is the first listed.

NCT05523817 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05523817 about?

NCT05523817 is a clinical study titled "Targeting Specific Brain Networks to Treat Specific Symptoms in Depression". Repetitive transcranial magnetic stimulation (rTMS) is a way of non-invasively stimulating specific brain networks and is an established treatment for Major Depressive Disorder (MDD). This proposal will reveal network mechanisms of the therapeutic effects of rTMS by investigating how stimulating eac...

What is the current status of trial NCT05523817?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2024-03-12. Estimated completion is 2028-12-31.

What conditions does trial NCT05523817 study?

This clinical trial studies the following conditions: Major Depressive Disorder.

What interventions are being tested in trial NCT05523817?

The interventions under investigation include: Intermittent Theta Burst Stimulation (iTBS) (DEVICE).

Who is sponsoring clinical trial NCT05523817?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05523817 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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