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Children's Bipolar Network Treatment Trial I
NCT05427123 · View on ClinicalTrials.gov ↗
Study Summary
This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN). CBN sites have expertise in diagnosing, assessing, and treating BSDs in youth. The primary aims of this study are to (1) identify and reliably diagnose youth (ages 9 to 19 yrs) with full bipolar disorder (BD) and BSDs, and (2) examine predictors (e.g., mood instability, inflammatory marker C-reactive protein) of clinical outcome over a 12 month period. Participating youth will initially complete a screening that includes a structured diagnostic interview and a baseline blood draw to measure inflammatory processes. Youth with BSD and parents (80 families) will be asked to participate in multiple follow up research visits with interviews, rating instruments, and questionnaires. Per established CBN guidelines, study psychiatrists will provide and track medication management and sites will also track psychosocial treatments. This study ultimately aims to further understanding of best practice pediatric BSD psychiatric and psychosocial treatments and development of a standardized and validated set of clinical tools for patient assessment, diagnosis, and tracking.
Conditions Studied
Interventions
- OTHER Medication or psychosocial treatment
Study Locations (4)
California
- University of California, Los Angeles, Max Gray Child and Adolescent Mood Disorders Program (CHAMP) — Los Angeles
Colorado
- University of Colorado Anschutz Medical Campus, Helen and Arthur E. Johnson Depression Center — Aurora
Pennsylvania
- University of Pittsburgh Child and Adolescent Bipolar Spectrum Services Clinic (CABS) — Pittsburgh
Virginia
- Virginia Commonwealth University Medical Center — Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2022-07-01 |
| Est. Completion | 2027-07-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05427123
The ClinicalTrials.gov registry entry for NCT05427123 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Los Angeles, which has 829 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 7 conditions, with Bipolar Disorder appearing as the primary indexed condition, and to 1 intervention — of which Medication or psychosocial treatment is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05427123 reports 4 study locations spanning 4 distinct geographic areas — top geographies include California, Colorado, Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05427123 about?
NCT05427123 is a clinical study titled "Children's Bipolar Network Treatment Trial I". This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN). CBN sites have expertise in diagnosing, assessing, and treating BSDs in youth. The primary aims of this study are to (1) identify and reli...
What is the current status of trial NCT05427123?
This trial is currently recruiting. The enrollment target is 80 participants. The study started on 2022-07-01. Estimated completion is 2027-07-01.
What conditions does trial NCT05427123 study?
This clinical trial studies the following conditions: Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder, Adolescent - Emotional Problem, Child Mental Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05427123?
The interventions under investigation include: Medication or psychosocial treatment (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05427123?
This trial is sponsored by University of California, Los Angeles, which has 829 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05427123 being conducted?
This trial has 4 study locations across California, Colorado, Pennsylvania, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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