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RECRUITING Phase 4

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

NCT07105111 · View on ClinicalTrials.gov ↗

Study Summary

This study will evaluate the efficacy of valbenazine on clinician- and patient-reported outcomes in participants with TD while receiving or after stopping a VMAT2 inhibitor.

Interventions

  • DRUG Valbenazine

Study Locations (8)

Florida

  • Neurocrine Clinical Site — Bonita Springs
  • Neurocrine Clinical Site — Hialeah
  • Neurocrine Clinical Site — Miami
  • Neurocrine Clinical Site — Tampa

California

  • Neurocrine Clinical Site — Fountain Valley
  • Neurocrine Clinical Site — Orange

Arkansas

  • Neurocrine Clinical Site — Bryant

Georgia

  • Neurocrine Clinical Site — Marietta

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2025-08-29
Est. Completion 2027-04
Phase Phase 4

Sponsor

Neurocrine Biosciences

47 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07105111

The ClinicalTrials.gov registry entry for NCT07105111 describes a study currently listed as recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Neurocrine Biosciences, which has 47 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Schizophrenia appearing as the primary indexed condition, and to 1 intervention — of which Valbenazine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07105111 reports 8 study locations spanning 4 distinct geographic areas — top geographies include Florida, California, Arkansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07105111 about?

NCT07105111 is a clinical study titled "A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor". This study will evaluate the efficacy of valbenazine on clinician- and patient-reported outcomes in participants with TD while receiving or after stopping a VMAT2 inhibitor.

What is the current status of trial NCT07105111?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2025-08-29. Estimated completion is 2027-04.

What conditions does trial NCT07105111 study?

This clinical trial studies the following conditions: Schizophrenia, Major Depressive Disorder, Bipolar Disorder, Schizoaffective Disorder, Tardive Dyskinesia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07105111?

The interventions under investigation include: Valbenazine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07105111?

This trial is sponsored by Neurocrine Biosciences, which has 47 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07105111 being conducted?

This trial has 8 study locations across Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial