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NCT05327504 · ClinicalTrials.gov registry record · NA
Written Exposure Therapy for Veterans With SUD and PTSD
A NA study of Post Traumatic Stress Disorder and Substance Use Disorders, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 170
- Enrollment target
- 1
- Study location
NCT05327504: Recruiting NA study of Post Traumatic Stress Disorder and Substance Use Disorders, sponsored by VA Office of Research and Development.
NCT05327504 is a NA study of Post Traumatic Stress Disorder and Substance Use Disorders that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 170 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05327504, a NA study of Post Traumatic Stress Disorder and Substance Use Disorders, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 170 participants
- Enrollment target
- 1
- Study location
Study Summary
The proposed project will evaluate the efficacy of written exposure therapy (WET) among Veterans engaged in substance use disorder (SUD) treatment, who present with co-occurring posttraumatic stress disorder (PTSD). While SUD treatment programs traditionally do not address PTSD, effective trauma treatments have been used successfully among those with substance use comorbidities. WET is a brief trauma-focused intervention shown to effectively treat PTSD. In a recent acceptability and feasibility pilot study among Veterans with co-occurring SUD and PTSD, results showed a decrease in PTSD symptoms among participants receiving WET. The goal of the present study is to improve outcomes for Veterans who present for SUD treatment with comorbid SUD/PTSD.
Primary Outcome
PTSD Checklist for DSM-5 (PCL-5) will be used to collect information on PTSD symptoms. The PCL-5 for DSM-5 is a 20-item self-report measure, selected for its dimensional sensitivity, with higher scores reflecting greater PTSD severity. Scoring is based on how much the patient has been bothered by the symptoms on a scale from "0 = not at all" to "4 = extremely." PCL scores will be collected based upon symptoms experienced in the past month at Baseline as well as each Post-Baseline Follow-up (8-we
Conditions Studied
Interventions
- BEHAVIORAL Written Exposure Therapy
- BEHAVIORAL Neutral Topic Writing
Study Locations (1)
Connecticut
- VA Connecticut Healthcare System West Haven Campus, West Haven, CT - West Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 2022-09-26 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
What NCT05327504 shows while recruiting
NCT05327504 is an interventional study that assigns participants to a tested intervention. The registered 170 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (74% lower).
The record links to 2 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which Written Exposure Therapy is the first listed.
NCT05327504 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT05327504 about?
NCT05327504 is a clinical study titled "Written Exposure Therapy for Veterans With SUD and PTSD". The proposed project will evaluate the efficacy of written exposure therapy (WET) among Veterans engaged in substance use disorder (SUD) treatment, who present with co-occurring posttraumatic stress disorder (PTSD). While SUD treatment programs traditionally do not address PTSD, effective trauma tre...
What is the current status of trial NCT05327504?
This trial is currently recruiting. It is a NA study. The enrollment target is 170 participants. The study started on 2022-09-26. Estimated completion is 2027-06-30.
What conditions does trial NCT05327504 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Substance Use Disorders.
What interventions are being tested in trial NCT05327504?
The interventions under investigation include: Written Exposure Therapy (BEHAVIORAL), Neutral Topic Writing (BEHAVIORAL).
Who is sponsoring clinical trial NCT05327504?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05327504 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Traumatic Stress Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05327504's enrollment target sits among peer trials
170 70th of 262 higher than 192 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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