Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05177822 · ClinicalTrials.gov registry record · Phase 2

Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart Failure

A Phase 2 study of Heart Failure, sponsored by Virginia Commonwealth University.

Recruiting
Registry status
Phase 2
Development phase
84
Enrollment target
2
Study locations

NCT05177822 is a Phase 2 study of Heart Failure that is actively recruiting participants, run by Virginia Commonwealth University. The registered enrollment target is 84 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05177822, a Phase 2 study of Heart Failure, is actively recruiting participants, sponsored by Virginia Commonwealth University.

RECRUITING
Registry status
Phase 2
Development phase
84 participants
Enrollment target
2
Study locations

Study Summary

Patients who have a heart attack are at high risk for future development of heart failure ('weakening of the heart'). The researchers believe that the reaction of the heart muscle to injury (inflammation) during a heart attack may be contributing to the risk of heart failure. The current study will test the ability of an anti-inflammatory medicine (anakinra) to block the inflammation in the body during and after a heart attack.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Anakinra

Study Locations (2)

Virginia

  • University of Virginia - Charlottesville
  • Virginia Commonwealth University - Richmond

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2022-05-24
Est. Completion 2027-12-30
Phase Phase 2

Sponsor

Virginia Commonwealth University

558 total trials

What the Registry Record Tells You About NCT05177822

The ClinicalTrials.gov registry entry for NCT05177822 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 84 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (96% lower). The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05177822 reports 2 study locations spanning 1 distinct geographic area - top geographies include Virginia.

Frequently Asked Questions

What is clinical trial NCT05177822 about?

NCT05177822 is a clinical study titled "Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart Failure". Patients who have a heart attack are at high risk for future development of heart failure ('weakening of the heart'). The researchers believe that the reaction of the heart muscle to injury (inflammation) during a heart attack may be contributing to the risk of heart failure. The current study will ...

What is the current status of trial NCT05177822?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2022-05-24. Estimated completion is 2027-12-30.

What conditions does trial NCT05177822 study?

This clinical trial studies the following conditions: Heart Failure.

What interventions are being tested in trial NCT05177822?

The interventions under investigation include: Placebo (OTHER), Anakinra (DRUG).

Who is sponsoring clinical trial NCT05177822?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05177822 being conducted?

This trial has 2 study locations across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Heart Failure

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.