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NCT02391519 · ClinicalTrials.gov registry record

Effects of High Altitude on AMPK Activation

A clinical trial of Pregnancy and Preeclampsia, sponsored by University of Colorado, Denver.

Recruiting
Registry status
84
Enrollment target
1
Study location

NCT02391519 is a study of Pregnancy and Preeclampsia that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 84 participants, below the 872-participant average among 191 other Pregnancy trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02391519, a study of Pregnancy and Preeclampsia, is actively recruiting participants, sponsored by University of Colorado, Denver.

RECRUITING
Registry status
84 participants
Enrollment target
1
Study location

Study Summary

Pregnancy elicits adaptive changes in uteroplacental blood flow, which are altered at high altitude and may contribute to the observed 3-fold increase in intrauterine growth restriction (IUGR) and preeclampsia (PreE). The investigators propose to collect myometrial, cord blood, and placental tissue samples from women at high altitude (Summit County) and low altitude (Denver) in Colorado in order to determine if residence at altitude during pregnancy changes the vasoreactivity of myometrial arteries (MA). If altered MA vasoreactivity is found, further studies may be able to link these changes to the increased rates of PreE and IUGR at altitude and contribute to the understanding of these two disorders.

Interventions

  • PROCEDURE Collection of myometrial, cord blood, and placental tissue samples

Study Locations (1)

Colorado

  • University of Colorado Denver Anschutz Medical Campus - Aurora

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2016-01
Est. Completion 2026-12-31

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT02391519

The ClinicalTrials.gov registry entry for NCT02391519 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 84 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 872-participant average among 191 other Pregnancy trials with a reported enrollment target (90% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Pregnancy appearing as the primary indexed condition, and to 1 intervention - of which Collection of myometrial, cord blood, and placental tissue samples is the first listed.

NCT02391519 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT02391519 about?

NCT02391519 is a clinical study titled "Effects of High Altitude on AMPK Activation". Pregnancy elicits adaptive changes in uteroplacental blood flow, which are altered at high altitude and may contribute to the observed 3-fold increase in intrauterine growth restriction (IUGR) and preeclampsia (PreE). The investigators propose to collect myometrial, cord blood, and placental tissue ...

What is the current status of trial NCT02391519?

This trial is currently recruiting. The enrollment target is 84 participants. The study started on 2016-01. Estimated completion is 2026-12-31.

What conditions does trial NCT02391519 study?

This clinical trial studies the following conditions: Pregnancy, Preeclampsia, IUGR.

What interventions are being tested in trial NCT02391519?

The interventions under investigation include: Collection of myometrial, cord blood, and placental tissue samples (PROCEDURE).

Who is sponsoring clinical trial NCT02391519?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02391519 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.