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NCT05145595 · ClinicalTrials.gov registry record · NA
Pain Sensitivity During Puberty
A NA study of Pain, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT05145595: Completed NA study of Pain, sponsored by Washington University School of Medicine.
NCT05145595 is a NA study of Pain that has completed, run by Washington University School of Medicine. The registered enrollment target is 36 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05145595, a NA study of Pain, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
Aim 1- To examine the differences in pain sensitivity between adolescents at early vs. mid pubertal status Aim 2- To determine the relationships between sex hormone levels and pain sensitivity Exploratory Aim 1- To determine the effect of pubertal maturation on pain sensitivity Exploratory Aim 2- To identify parameters related to who will develop chronic pain during puberty Hypothesis 1- Adolescents in early pubertal status will have higher pain ratings and lower pain modulation capabilities compared to adolescents in mid puberal status. Hypothesis 2- Pain sensitivity will be associated with sex hormone levels. Exploratory Hypothesis 1- As adolescents mature, they will have a decrease in pain sensitivity to experimental pain which will be related to changes in sex hormone levels. Exploratory hypothesis 2- Female adolescents with greater pain sensitivity, lower testosterone levels and with a family history of pain would be at a higher risk to develop chronic pain
Primary Outcome
A 30-second tonic heat pain at the intensity of 46°C will be delivered to the volar forearm. During the heat stimulus, pain intensity ratings will be obtained.
Conditions Studied
Interventions
- DEVICE Thermal Sensory Analyzer
- DEVICE Pressure Stimuli
- DEVICE Mechanical Stimuli
- BEHAVIORAL Pain Ratings
- BEHAVIORAL Thermal pain thresholds
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2022-09-20 |
| Est. Completion | 2024-07-17 |
| Phase | NA |
What the finished NCT05145595 record still lists
NCT05145595 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (88% lower).
The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 5 interventions - of which Thermal Sensory Analyzer is the first listed.
NCT05145595 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT05145595 about?
NCT05145595 is a clinical study titled "Pain Sensitivity During Puberty". Aim 1- To examine the differences in pain sensitivity between adolescents at early vs. mid pubertal status Aim 2- To determine the relationships between sex hormone levels and pain sensitivity Exploratory Aim 1- To determine the effect of pubertal maturation on pain sensitivity Exploratory Aim 2- To...
What is the current status of trial NCT05145595?
This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2022-09-20. Estimated completion is 2024-07-17.
What conditions does trial NCT05145595 study?
This clinical trial studies the following conditions: Pain.
What interventions are being tested in trial NCT05145595?
The interventions under investigation include: Thermal Sensory Analyzer (DEVICE), Pressure Stimuli (DEVICE), Mechanical Stimuli (DEVICE), Pain Ratings (BEHAVIORAL), Thermal pain thresholds (BEHAVIORAL).
Who is sponsoring clinical trial NCT05145595?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05145595 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05145595's enrollment target sits among peer trials
36 296th of 374 higher than 77 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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