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NCT05027919 · ClinicalTrials.gov registry record · Phase 2

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

A Phase 2 study of Opioid Use Disorder and Opioid Withdrawal, sponsored by University of Maryland, Baltimore.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target
1
Study location

NCT05027919 is a Phase 2 study of Opioid Use Disorder and Opioid Withdrawal that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 60 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05027919, a Phase 2 study of Opioid Use Disorder and Opioid Withdrawal, is actively recruiting participants, sponsored by University of Maryland, Baltimore.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

Evaluate individual differences in the expression of opioid withdrawal symptoms in persons with opioid use disorder (OUD) while completing a clinically-indicated medication taper.

Conditions Studied

Opioid Use Disorder Opioid Withdrawal Opioid Craving

Interventions

  • DRUG Hydromorphone
  • DRUG Lofexidine
  • DRUG Naloxone + lofexidine pretreatment
  • DRUG Naloxone + placebo pretreatment

Study Locations (1)

Maryland

  • University of Maryland - Baltimore

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2021-12-01
Est. Completion 2027-02-28
Phase Phase 2

Sponsor

University of Maryland, Baltimore

560 total trials

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What the Registry Record Tells You About NCT05027919

The ClinicalTrials.gov registry entry for NCT05027919 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (99% lower). The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 4 interventions - of which Hydromorphone is the first listed.

NCT05027919 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT05027919 about?

NCT05027919 is a clinical study titled "Assessing a Clinically-meaningful Opioid Withdrawal Phenotype". Evaluate individual differences in the expression of opioid withdrawal symptoms in persons with opioid use disorder (OUD) while completing a clinically-indicated medication taper.

What is the current status of trial NCT05027919?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2021-12-01. Estimated completion is 2027-02-28.

What conditions does trial NCT05027919 study?

This clinical trial studies the following conditions: Opioid Use Disorder, Opioid Withdrawal, Opioid Craving.

What interventions are being tested in trial NCT05027919?

The interventions under investigation include: Hydromorphone (DRUG), Lofexidine (DRUG), Naloxone + lofexidine pretreatment (DRUG), Naloxone + placebo pretreatment (DRUG).

Who is sponsoring clinical trial NCT05027919?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05027919 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.