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NCT06718491 · ClinicalTrials.gov registry record · Phase 2

Brief Digitally-Enhanced Intervention for Reducing Alcohol Use During MOUD

A Phase 2 study of Opioid Use Disorder, sponsored by Ohio State University.

Recruiting
Registry status
Phase 2
Development phase
80
Enrollment target
1
Study location

NCT06718491 is a Phase 2 study of Opioid Use Disorder that is actively recruiting participants, run by Ohio State University. The registered enrollment target is 80 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06718491, a Phase 2 study of Opioid Use Disorder, is actively recruiting participants, sponsored by Ohio State University.

RECRUITING
Registry status
Phase 2
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to reduce heavy drinking and enhance medication for opioid use disorder (MOUD) outcomes in individuals receiving MOUD. The main questions it aims to answer are: * Does the brief, digitally-enhanced, virtual psychotherapeutic intervention, called Managing Physical Reactions to Overwhelming Emotions (IMPROVE), impact daily alcohol use and MOUD adherence? * Does the intervention change self-report and physiological responses to intolerance to uncertainty and anxiety sensitivity? Researchers will compare IMPROVE to a control intervention (health education treatment) to see if IMPROVE impacts daily alcohol use and MOUD adherence. Participants will: * Complete a baseline electroencephalography (EEG) and self-report questionnaires. * Complete three one-hour intervention sessions (IMPROVE or control) each one week a part. * Complete a post-intervention EEG and self-report questionnaires. * Complete five ecological momentary assessment (EMA) surveys a day for 21 days. * Complete self-report questionnaires one-month after their last intervention session.

Conditions Studied

Opioid Use Disorder

Interventions

  • BEHAVIORAL Managing Physical Reactions to Overwhelming Emotions (IMPROVE)
  • BEHAVIORAL Health Education Training (HET)

Study Locations (1)

Ohio

  • Ohio State University - Columbus

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2025-08-01
Est. Completion 2027-07
Phase Phase 2

Sponsor

Ohio State University

552 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06718491

The ClinicalTrials.gov registry entry for NCT06718491 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (98% lower). The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Opioid Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Managing Physical Reactions to Overwhelming Emotions (IMPROVE) is the first listed.

NCT06718491 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT06718491 about?

NCT06718491 is a clinical study titled "Brief Digitally-Enhanced Intervention for Reducing Alcohol Use During MOUD". The goal of this clinical trial is to reduce heavy drinking and enhance medication for opioid use disorder (MOUD) outcomes in individuals receiving MOUD. The main questions it aims to answer are: * Does the brief, digitally-enhanced, virtual psychotherapeutic intervention, called Managing Physical ...

What is the current status of trial NCT06718491?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2025-08-01. Estimated completion is 2027-07.

What conditions does trial NCT06718491 study?

This clinical trial studies the following conditions: Opioid Use Disorder.

What interventions are being tested in trial NCT06718491?

The interventions under investigation include: Managing Physical Reactions to Overwhelming Emotions (IMPROVE) (BEHAVIORAL), Health Education Training (HET) (BEHAVIORAL).

Who is sponsoring clinical trial NCT06718491?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06718491 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.