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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Opioid Craving: early-phase trial registry

2 of 3 indexed Opioid Craving trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #5,209 of 28,707 conditions by registered trial count.

3 US clinical trials · 2 currently recruiting · #5,209 of 28,707 conditions by registered trial count

Opioid Craving: 3 US clinical trials tracked, 2 recruiting.

Opioid Craving is the subject of 3 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 2 of these trials.

Enrollment posture brief

Registry condition opioid-craving

OPEN 2 | RECR 67% | LATE 0 | EARLY 2 | RANK #5209 | SPON 2

Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)

Ablation80%ACL Reconstruction80%Opioid Craving (this)67%Abuse, Drug60%Acceptability60%
Open-enrollment share among volume-matched conditions near Opioid Craving

Opioid Craving lists 2 open slots (67% of 3 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Opioid Craving on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Opioid Craving is recruiting above its size-band peers.

    2 of 3 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

Phase 22

Phase Distribution

PhaseTrial count
Phase 2 2

Named interventions

Most-linked intervention names on Opioid Craving records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Lofexidine Drug
2 trials
Naloxone + placebo pretreatment Drug
1 trials
Naloxone + lofexidine pretreatment Drug
1 trials
Visual and Tactile Opioid Cue-induced Craving Behavioral
1 trials
Visual Opioid Cue-induced Craving Behavioral
1 trials
Neutral Cue-induced Craving Behavioral
1 trials
Buspirone Drug
1 trials
Hydromorphone Drug
1 trials

US sites by state

Facility locations filed on Opioid Craving trials. A trial with sites in several states counts in each.

Maryland 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Opioid Craving page

3 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Opioid Craving condition card totals 3 registered trials; most-linked intervention Lofexidine; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.