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NCT04872998 · ClinicalTrials.gov registry record · NA
Vascular Dysfunction During Physical Inactivity
A NA study of Aging and Skeletal Muscle, sponsored by University of Utah.
- Completed
- Registry status
- NA
- Development phase
- 14
- Enrollment target
- 1
- Study location
NCT04872998 is a NA study of Aging and Skeletal Muscle that has completed, run by University of Utah. The registered enrollment target is 14 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04872998, a NA study of Aging and Skeletal Muscle, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
Prolonged periods of reduced activity are associated with decreased vascular function and muscle atrophy. Physical inactivity due to a sedentary lifestyle or acute hospitalization is also associated with impaired recovery, hospital readmission, and increased mortality. Older adults are a particularly vulnerable population as functional (vascular and skeletal muscle mitochondrial dysfunction) and structural deficits (loss in muscle mass leading to a reduction in strength) are a consequence of the aging process. The combination of inactivity and aging poses an added health threat to these individuals by accelerating the negative impact on vascular and skeletal muscle function and dysfunction. The underlying factors leading to vascular and skeletal muscle dysfunction are unknown, but have been linked to increases in oxidative stress. Additionally, there is a lack of understanding of how vascular function is impacted by inactivity in humans and how these changes are related to skeletal muscle function. It is the goal of this study to investigate the mechanisms that contribute to disuse muscle atrophy and vascular dysfunction in order to diminish their negative impact, and preserve vascular and skeletal muscle function.
Conditions Studied
Interventions
- BEHAVIORAL Step Count Reduction
Study Locations (1)
Utah
- VA Medical Center Building - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2019-03-15 |
| Est. Completion | 2021-03-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04872998
The ClinicalTrials.gov registry entry for NCT04872998 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 1 intervention - of which Step Count Reduction is the first listed.
NCT04872998 reports 1 study location spanning 1 distinct geographic area - top geographies include Utah.
Frequently Asked Questions
What is clinical trial NCT04872998 about?
NCT04872998 is a clinical study titled "Vascular Dysfunction During Physical Inactivity". Prolonged periods of reduced activity are associated with decreased vascular function and muscle atrophy. Physical inactivity due to a sedentary lifestyle or acute hospitalization is also associated with impaired recovery, hospital readmission, and increased mortality. Older adults are a particularl...
What is the current status of trial NCT04872998?
This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2019-03-15. Estimated completion is 2021-03-31.
What conditions does trial NCT04872998 study?
This clinical trial studies the following conditions: Aging, Skeletal Muscle, Vascular Endothelium.
What interventions are being tested in trial NCT04872998?
The interventions under investigation include: Step Count Reduction (BEHAVIORAL).
Who is sponsoring clinical trial NCT04872998?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04872998 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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