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NCT04699773 · ClinicalTrials.gov registry record · NA
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
A NA study of Glioblastoma and Glioma, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- NA
- Development phase
- 32
- Enrollment target
- 5
- Study locations
NCT04699773: Recruiting NA study of Glioblastoma and Glioma, sponsored by University of Maryland, Baltimore.
NCT04699773 is a NA study of Glioblastoma and Glioma that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 32 participants, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (71% lower). The trial reports 5 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04699773, a NA study of Glioblastoma and Glioma, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this study is to evaluate the treatment regimen of using Laser Interstitial Thermal Therapy (LITT) and Hypo-fractionated Radiation Therapy to treat patients with newly diagnosed gliomas.
Primary Outcome
The ability to complete protocol treatment (i.e. LITT and radiation therapy) without undue treatment-related acute toxicity as defined below: * Safety: \< 40% rate of irreversible Grade 3 or higher neurologic treatment-related toxicity * Early stopping rules: Two or more Grade 2 or higher symptomatic CNS hemorrhages; Eight treatment-related Grade 3 or higher non-hematologic or Grade 4 or higher hematologic treatment related toxicities
Conditions Studied
Interventions
- RADIATION Hypofractionated Radiation Therapy
- PROCEDURE LITT
Study Locations (5)
Maryland
- Maryland Proton Treatment Center - Baltimore
- University of Maryland Greenebaum Cancer Center - Baltimore
- UCH Kaufman Cancer Center - Bel Air
- Central Maryland Radiation Oncology - Columbia
- Baltimore Washington Medical Center - Glen Burnie
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2021-02-20 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT04699773 shows while recruiting
NCT04699773 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (71% lower).
The record links to 3 conditions, with Glioblastoma appearing as the primary indexed condition, and to 2 interventions - of which Hypofractionated Radiation Therapy is the first listed.
NCT04699773 lists 5 locations in 1 state (Maryland).
Frequently Asked Questions
What is clinical trial NCT04699773 about?
NCT04699773 is a clinical study titled "LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)". The purpose of this study is to evaluate the treatment regimen of using Laser Interstitial Thermal Therapy (LITT) and Hypo-fractionated Radiation Therapy to treat patients with newly diagnosed gliomas.
What is the current status of trial NCT04699773?
This trial is currently recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2021-02-20. Estimated completion is 2027-12.
What conditions does trial NCT04699773 study?
This clinical trial studies the following conditions: Glioblastoma, Glioma, Brain Tumor.
What interventions are being tested in trial NCT04699773?
The interventions under investigation include: Hypofractionated Radiation Therapy (RADIATION), LITT (PROCEDURE).
Who is sponsoring clinical trial NCT04699773?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04699773 being conducted?
This trial has 5 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Glioblastoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04699773's enrollment target sits among peer trials
32 121st of 199 higher than 77 of 199 other Glioblastoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Glioblastoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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LITT Followed by Hypofractionated RT for Recurrent Gliomas
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