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NCT05281731 · ClinicalTrials.gov registry record · NA
Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma
A NA study of Glioblastoma and Glioblastoma Multiforme, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05281731: Recruiting NA study of Glioblastoma and Glioblastoma Multiforme, sponsored by Washington University School of Medicine.
NCT05281731 is a NA study of Glioblastoma and Glioblastoma Multiforme that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 40 participants, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05281731, a NA study of Glioblastoma and Glioblastoma Multiforme, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This clinical study to evaluate sonobiopsy is significant because sonobiopsy will fundamentally enhance the clinician's insight into the molecular features of an intracranial lesion to tailor treatment approaches and optimize outcomes. In addition to the standard diagnostics of anatomic imaging and surgical histology, sonobiopsy has the potential to become the third pillar for brain tumor management by radically advancing the ability to easily and regularly acquire tumor genetic and molecular signatures. This enhanced capability will have a dramatic impact on patient survival and quality of life.
Primary Outcome
The feasibility of sonobiopsy will be demonstrated by an increase in the amount of ctDNA in the blood samples acquired post than prior sonobiopsy in at least 50% of the patients.
Conditions Studied
Interventions
- DEVICE Sonobiopsy
- PROCEDURE Research blood
- GENETIC Cancer Personalized Profiling
- DEVICE Definity®
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2022-04-18 |
| Est. Completion | 2028-11-30 |
| Phase | NA |
What NCT05281731 shows while recruiting
NCT05281731 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (63% lower).
The record links to 2 conditions, with Glioblastoma appearing as the primary indexed condition, and to 4 interventions - of which Sonobiopsy is the first listed.
NCT05281731 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT05281731 about?
NCT05281731 is a clinical study titled "Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma". This clinical study to evaluate sonobiopsy is significant because sonobiopsy will fundamentally enhance the clinician's insight into the molecular features of an intracranial lesion to tailor treatment approaches and optimize outcomes. In addition to the standard diagnostics of anatomic imaging and ...
What is the current status of trial NCT05281731?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2022-04-18. Estimated completion is 2028-11-30.
What conditions does trial NCT05281731 study?
This clinical trial studies the following conditions: Glioblastoma, Glioblastoma Multiforme.
What interventions are being tested in trial NCT05281731?
The interventions under investigation include: Sonobiopsy (DEVICE), Research blood (PROCEDURE), Cancer Personalized Profiling (GENETIC), Definity® (DEVICE).
Who is sponsoring clinical trial NCT05281731?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05281731 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Glioblastoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05281731's enrollment target sits among peer trials
40 103rd of 199 higher than 94 of 199 other Glioblastoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Glioblastoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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