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LITES Task Order 0005 Prehospital Airway Control Trial (PACT)
NCT04100564 · View on ClinicalTrials.gov ↗
Study Summary
The Prehospital Airway Control Trial (PACT) is a proposed 5 year, open label, multi-center, stepped-wedge randomized trial comparing airway management strategies of prehospital trauma patients. The initial airway attempt will be randomized to either usual care (control) or a supraglottic airway management approach (intervention). The primary outcome will be 24 hour survival, with secondary outcomes to include survival to hospital discharge, expected clinical adverse events, airway management performance, ICU length of stay, ventilator days, incidence of ARDS, and incidence of ventilator associated pneumonia. Subjects will be enrolled across approximately 17 prehospital agencies at select LITES Network sites and will enroll a total of 2,009 subjects.
Conditions Studied
Interventions
- DEVICE Supraglottic airway device
- OTHER Standard airway management
Study Locations (14)
Illinois
- Mount Sinai Hospital — Chicago
- Northwestern Memorial Hospital — Chicago
- John H. Stroger Hospital of Cook County — Chicago
- University of Chicago — Chicago
Pennsylvania
- Allegheny General Hospital — Pittsburgh
- University of Pittsburgh — Pittsburgh
- UPMC — Pittsburgh
Georgia
- Emory University — Atlanta
Kentucky
- University of Louisville — Louisville
Louisiana
- Tulane University — New Orleans
Missouri
- Washington University at St. Louis — St Louis
North Carolina
- East Carolina University — Greenville
Oregon
- Oregon Health & Science University — Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,009 participants |
| Start Date | 2021-04-01 |
| Est. Completion | 2027-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04100564
The ClinicalTrials.gov registry entry for NCT04100564 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2,009 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jason Sperry, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Trauma Injury appearing as the primary indexed condition, and to 2 interventions — of which Supraglottic airway device is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04100564 reports 14 study locations spanning 9 distinct geographic areas — top geographies include Illinois, Pennsylvania, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04100564 about?
NCT04100564 is a clinical study titled "LITES Task Order 0005 Prehospital Airway Control Trial (PACT)". The Prehospital Airway Control Trial (PACT) is a proposed 5 year, open label, multi-center, stepped-wedge randomized trial comparing airway management strategies of prehospital trauma patients. The initial airway attempt will be randomized to either usual care (control) or a supraglottic airway mana...
What is the current status of trial NCT04100564?
This trial is currently recruiting. It is a NA study. The enrollment target is 2,009 participants. The study started on 2021-04-01. Estimated completion is 2027-01.
What conditions does trial NCT04100564 study?
This clinical trial studies the following conditions: Trauma Injury, Airway Control. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04100564?
The interventions under investigation include: Supraglottic airway device (DEVICE), Standard airway management (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04100564?
This trial is sponsored by Jason Sperry, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04100564 being conducted?
This trial has 14 study locations across Georgia, Illinois, Kentucky, Louisiana, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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