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NCT04500847 · ClinicalTrials.gov registry record · Phase 1
Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
A Phase 1 study of Mild Cognitive Impairment and Alzheimer Disease, Early Onset, sponsored by Butler Hospital.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 35
- Enrollment target
- 2
- Study locations
NCT04500847 is a Phase 1 study of Mild Cognitive Impairment and Alzheimer Disease, Early Onset that is actively recruiting participants, run by Butler Hospital. The registered enrollment target is 35 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT04500847, a Phase 1 study of Mild Cognitive Impairment and Alzheimer Disease, Early Onset, is actively recruiting participants, sponsored by Butler Hospital.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 35 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is a randomized, double-blind clinical trial of a daily oral dose of 200 mg emtricitabine vs. placebo in 35 participants with biomarker-confirmed MCI or mild to moderate dementia due to Alzheimer's disease. Study duration for each subject participating in the placebo-controlled research study will be approximately 12 months (up to a 3 months Screening Period, Baseline visit (1 month), 6 months of placebo or emtricitabine dosing, and 1 month follow-up). Participants will have up to 2 months to complete all procedures for the month 6 study visit.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Emtriva Capsule
Study Locations (2)
California
- Cedars-Sinai Medical Center - Los Angeles
Rhode Island
- Memory and Aging Program, Butler Hospital - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2021-12-17 |
| Est. Completion | 2026-03-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04500847
The ClinicalTrials.gov registry entry for NCT04500847 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (97% lower). The listed sponsor is Butler Hospital, which has 103 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04500847 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Rhode Island.
Frequently Asked Questions
What is clinical trial NCT04500847 about?
NCT04500847 is a clinical study titled "Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD". This is a randomized, double-blind clinical trial of a daily oral dose of 200 mg emtricitabine vs. placebo in 35 participants with biomarker-confirmed MCI or mild to moderate dementia due to Alzheimer's disease. Study duration for each subject participating in the placebo-controlled research study w...
What is the current status of trial NCT04500847?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2021-12-17. Estimated completion is 2026-03-31.
What conditions does trial NCT04500847 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment, Alzheimer Disease, Early Onset, Moderate Dementia.
What interventions are being tested in trial NCT04500847?
The interventions under investigation include: Placebo (DRUG), Emtriva Capsule (DRUG).
Who is sponsoring clinical trial NCT04500847?
This trial is sponsored by Butler Hospital, which has 103 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04500847 being conducted?
This trial has 2 study locations across California, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.