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NCT05591027 · ClinicalTrials.gov registry record · Phase 1

Safety and Target Engagement of Centella Asiatica in Cognitive Impairment

A Phase 1 study of Mild Cognitive Impairment and Alzheimers Disease, sponsored by Oregon Health and Science University.

Recruiting
Registry status
Phase 1
Development phase
48
Enrollment target
1
Study location

NCT05591027 is a Phase 1 study of Mild Cognitive Impairment and Alzheimers Disease that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 48 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05591027, a Phase 1 study of Mild Cognitive Impairment and Alzheimers Disease, is actively recruiting participants, sponsored by Oregon Health and Science University.

RECRUITING
Registry status
Phase 1
Development phase
48 participants
Enrollment target
1
Study location

Study Summary

This clinical trial is focused on determining whether biological signatures of target engagement by a Centella asiatica water extract product administered orally for 6 weeks can be measured in comparison to placebo. This study will also assess the safety and tolerability of the Centella asiatica water extract product.

Interventions

  • DRUG Placebo
  • DRUG Centella asiatica product

Study Locations (1)

Oregon

  • Oregon Health & Science University - Portland

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2022-12-01
Est. Completion 2026-03-31
Phase Phase 1

What the Registry Record Tells You About NCT05591027

The ClinicalTrials.gov registry entry for NCT05591027 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (96% lower). The listed sponsor is Oregon Health and Science University, which has 546 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05591027 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.

Frequently Asked Questions

What is clinical trial NCT05591027 about?

NCT05591027 is a clinical study titled "Safety and Target Engagement of Centella Asiatica in Cognitive Impairment". This clinical trial is focused on determining whether biological signatures of target engagement by a Centella asiatica water extract product administered orally for 6 weeks can be measured in comparison to placebo. This study will also assess the safety and tolerability of the Centella asiatica wat...

What is the current status of trial NCT05591027?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2022-12-01. Estimated completion is 2026-03-31.

What conditions does trial NCT05591027 study?

This clinical trial studies the following conditions: Mild Cognitive Impairment, Alzheimers Disease.

What interventions are being tested in trial NCT05591027?

The interventions under investigation include: Placebo (DRUG), Centella asiatica product (DRUG).

Who is sponsoring clinical trial NCT05591027?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05591027 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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