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NCT04428944 · ClinicalTrials.gov registry record · NA

STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation

A NA study of Atrial Fibrillation, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre.

Active
Registry status
NA
Development phase
617
Enrollment target
20
Study locations

NCT04428944 is a NA study of Atrial Fibrillation that is active but no longer recruiting, run by McGill University Health Centre/Research Institute of the McGill University Health Centre. The registered enrollment target is 617 participants, below the 2,994-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (79% lower). The trial reports 20 study locations across 8 states.

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The verdict

NCT04428944, a NA study of Atrial Fibrillation, is active but no longer recruiting, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
617 participants
Enrollment target
20
Study locations

Study Summary

The objective of this study is to compare the efficacy of three different ablation strategies in patients with persistent AF: 1. PV antral isolation alone (PVAI) 2. PV antral isolation plus ablation of drivers (PVAI+drivers) 3. PV antral isolation plus isolation of posterior wall (PVAI+box) All three strategies will employ contemporary catheter ablation technology using more efficient open irrigated tip cooling and contact force sensing.

Conditions Studied

Atrial Fibrillation

Interventions

  • PROCEDURE Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI)
  • PROCEDURE Pulmonary Vein Antrum Isolation Plus Driver Ablation (PVAI+drivers)
  • PROCEDURE Pulmonary Vein Antrum Isolation Plus Box Isolation of Posterior Wall (PVAI+box)

Study Locations (20)

Other

  • Royal Adelaide Hospital and Cardiovascular Centre - Adelaide
  • Alfred Health - Melbourne
  • Royal Melbourne Hospital - Parkville
  • Medical University of Graz - Graz
  • Ordensklinikum Linz GmbH - Linz
  • OLV Hospital Aalst - Aalst
  • Antwerp University Hospital (UZA) - Edegem
  • AZ Sint-Jan - Ruddershove

British Colombia

  • Vancouver General Hospital - Vancouver
  • St. Paul's Hospital, Vancouver, BC - Vancouver
  • Royal Jubilee Hospital - Victoria

Quebec

  • MUHC, McGill University Health Centre - Montreal
  • University of Ottawa Heart Institute - Ottawa
  • Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Québec

Ontario

  • Hamilton General Hospital - Hamilton
  • Southlake Regional Health Center - Newmarket

Massachusetts

  • Brigham & Women'S Hosptial Inc. - Boston

Australian Capital Territory

  • Canberra Heart Rhythm Foundation - Garran

Alberta

  • University of Calgary Foothills - Calgary

QC - Québec

  • Laurent Macle - Montreal

Trial Details

FieldValue
Enrollment Target 617 participants
Start Date 2021-06-01
Est. Completion 2027-12
Phase NA

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

9 total trials

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What the Registry Record Tells You About NCT04428944

The ClinicalTrials.gov registry entry for NCT04428944 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 617 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,994-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (79% lower). The listed sponsor is McGill University Health Centre/Research Institute of the McGill University Health Centre, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Atrial Fibrillation appearing as the primary indexed condition, and to 3 interventions - of which Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI) is the first listed.

NCT04428944 reports 20 study locations spanning 8 distinct geographic areas - top geographies include Other, British Colombia, Quebec.

Frequently Asked Questions

What is clinical trial NCT04428944 about?

NCT04428944 is a clinical study titled "STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation". The objective of this study is to compare the efficacy of three different ablation strategies in patients with persistent AF: 1. PV antral isolation alone (PVAI) 2. PV antral isolation plus ablation of drivers (PVAI+drivers) 3. PV antral isolation plus isolation of posterior wall (PVAI+box) All thr...

What is the current status of trial NCT04428944?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 617 participants. The study started on 2021-06-01. Estimated completion is 2027-12.

What conditions does trial NCT04428944 study?

This clinical trial studies the following conditions: Atrial Fibrillation.

What interventions are being tested in trial NCT04428944?

The interventions under investigation include: Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI) (PROCEDURE), Pulmonary Vein Antrum Isolation Plus Driver Ablation (PVAI+drivers) (PROCEDURE), Pulmonary Vein Antrum Isolation Plus Box Isolation of Posterior Wall (PVAI+box) (PROCEDURE).

Who is sponsoring clinical trial NCT04428944?

This trial is sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre, which has 9 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04428944 being conducted?

This trial has 20 study locations across Massachusetts, Australian Capital Territory, Alberta, British Colombia, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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