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NCT04428944 · ClinicalTrials.gov registry record · NA
STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation
A NA study of Atrial Fibrillation, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre.
- Active
- Registry status
- NA
- Development phase
- 617
- Enrollment target
- 20
- Study locations
NCT04428944: Active NA study of Atrial Fibrillation, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre.
NCT04428944 is a NA study of Atrial Fibrillation that is active but no longer recruiting, run by McGill University Health Centre/Research Institute of the McGill University Health Centre. The registered enrollment target is 617 participants, below the 2,994-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (79% lower). The trial reports 20 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04428944, a NA study of Atrial Fibrillation, is active but no longer recruiting, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 617 participants
- Enrollment target
- 20
- Study locations
Study Summary
The objective of this study is to compare the efficacy of three different ablation strategies in patients with persistent AF: 1. PV antral isolation alone (PVAI) 2. PV antral isolation plus ablation of drivers (PVAI+drivers) 3. PV antral isolation plus isolation of posterior wall (PVAI+box) All three strategies will employ contemporary catheter ablation technology using more efficient open irrigated tip cooling and contact force sensing.
Conditions Studied
Interventions
- PROCEDURE Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI)
- PROCEDURE Pulmonary Vein Antrum Isolation Plus Driver Ablation (PVAI+drivers)
- PROCEDURE Pulmonary Vein Antrum Isolation Plus Box Isolation of Posterior Wall (PVAI+box)
Study Locations (20)
Other
- Royal Adelaide Hospital and Cardiovascular Centre - Adelaide
- Alfred Health - Melbourne
- Royal Melbourne Hospital - Parkville
- Medical University of Graz - Graz
- Ordensklinikum Linz GmbH - Linz
- OLV Hospital Aalst - Aalst
- Antwerp University Hospital (UZA) - Edegem
- AZ Sint-Jan - Ruddershove
British Colombia
- Vancouver General Hospital - Vancouver
- St. Paul's Hospital, Vancouver, BC - Vancouver
- Royal Jubilee Hospital - Victoria
Quebec
- MUHC, McGill University Health Centre - Montreal
- University of Ottawa Heart Institute - Ottawa
- Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Québec
Ontario
- Hamilton General Hospital - Hamilton
- Southlake Regional Health Center - Newmarket
Massachusetts
- Brigham & Women'S Hosptial Inc. - Boston
Australian Capital Territory
- Canberra Heart Rhythm Foundation - Garran
Alberta
- University of Calgary Foothills - Calgary
QC - Québec
- Laurent Macle - Montreal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 617 participants |
| Start Date | 2021-06-01 |
| Est. Completion | 2027-12 |
| Phase | NA |
Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre9 total trials
What the registry record for NCT04428944 still lists
NCT04428944 is an interventional study that assigns participants to a tested intervention. The registered 617 participants enrollment target is mid-sized for trials with a published cap, below the 2,994-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Atrial Fibrillation appearing as the primary indexed condition, and to 3 interventions - of which Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI) is the first listed.
NCT04428944 names 20 study sites across 8 states, led by Other, British Colombia, Quebec.
Frequently Asked Questions
What is clinical trial NCT04428944 about?
NCT04428944 is a clinical study titled "STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation". The objective of this study is to compare the efficacy of three different ablation strategies in patients with persistent AF: 1. PV antral isolation alone (PVAI) 2. PV antral isolation plus ablation of drivers (PVAI+drivers) 3. PV antral isolation plus isolation of posterior wall (PVAI+box) All thr...
What is the current status of trial NCT04428944?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 617 participants. The study started on 2021-06-01. Estimated completion is 2027-12.
What conditions does trial NCT04428944 study?
This clinical trial studies the following conditions: Atrial Fibrillation.
What interventions are being tested in trial NCT04428944?
The interventions under investigation include: Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI) (PROCEDURE), Pulmonary Vein Antrum Isolation Plus Driver Ablation (PVAI+drivers) (PROCEDURE), Pulmonary Vein Antrum Isolation Plus Box Isolation of Posterior Wall (PVAI+box) (PROCEDURE).
Who is sponsoring clinical trial NCT04428944?
This trial is sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04428944 being conducted?
This trial has 20 study locations across Massachusetts, Australian Capital Territory, Alberta, British Colombia, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04428944's enrollment target sits among peer trials
617 49th of 202 higher than 154 of 202 other Atrial Fibrillation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Atrial Fibrillation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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