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NCT04322097 · ClinicalTrials.gov registry record · NA
Mechanisms of Upper Airway Obstruction
A NA study of Obstructive Sleep Apnea, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 133
- Enrollment target
- 1
- Study location
NCT04322097: Completed NA study of Obstructive Sleep Apnea, sponsored by University of Pennsylvania.
NCT04322097 is a NA study of Obstructive Sleep Apnea that has completed, run by University of Pennsylvania. The registered enrollment target is 133 participants, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (40% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04322097, a NA study of Obstructive Sleep Apnea, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 133 participants
- Enrollment target
- 1
- Study location
Study Summary
The current study is designed to examine underlying mechanisms of action of lingual muscles in the maintenance of airway patency during sleep. The investigators' major hypothesis is that specific tongue muscles are responsible for relieving upper airway obstruction during sleep.
Primary Outcome
Upper airway collapsibility (Pcrit, cmH₂O): Pressure at which the upper airway closes during inspiration, with a higher value indicating greater collapsibility. Pcrit less than zero indicates that the airway remains open. Pcrit greater than or equal to zero indicates that the airway is closed.
Conditions Studied
Interventions
- DEVICE Hypoglossal Nerve Stimulation
Study Locations (1)
Pennsylvania
- Pennsylvania Hospital - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 133 participants |
| Start Date | 2020-06-03 |
| Est. Completion | 2024-05-10 |
| Phase | NA |
What the finished NCT04322097 record still lists
NCT04322097 is an interventional study that assigns participants to a tested intervention. The registered 133 participants enrollment target is mid-sized for trials with a published cap, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (40% lower).
The record links to 1 condition, with Obstructive Sleep Apnea appearing as the primary indexed condition, and to 1 intervention - of which Hypoglossal Nerve Stimulation is the first listed.
NCT04322097 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04322097 about?
NCT04322097 is a clinical study titled "Mechanisms of Upper Airway Obstruction". The current study is designed to examine underlying mechanisms of action of lingual muscles in the maintenance of airway patency during sleep. The investigators' major hypothesis is that specific tongue muscles are responsible for relieving upper airway obstruction during sleep.
What is the current status of trial NCT04322097?
This trial is currently completed. It is a NA study. The enrollment target is 133 participants. The study started on 2020-06-03. Estimated completion is 2024-05-10.
What conditions does trial NCT04322097 study?
This clinical trial studies the following conditions: Obstructive Sleep Apnea.
What interventions are being tested in trial NCT04322097?
The interventions under investigation include: Hypoglossal Nerve Stimulation (DEVICE).
Who is sponsoring clinical trial NCT04322097?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04322097 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04322097's enrollment target sits among peer trials
133 56th of 155 higher than 100 of 155 other Obstructive Sleep Apnea trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obstructive Sleep Apnea trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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