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NCT07090395 · ClinicalTrials.gov registry record · NA

Severe Label Expansion for EVO Products Trial

A NA study of Obstructive Sleep Apnea, sponsored by ProSomnus Sleep Technologies.

Recruiting
Registry status
NA
Development phase
49
Enrollment target
2
Study locations

NCT07090395 is a NA study of Obstructive Sleep Apnea that is actively recruiting participants, run by ProSomnus Sleep Technologies. The registered enrollment target is 49 participants, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (78% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT07090395, a NA study of Obstructive Sleep Apnea, is actively recruiting participants, sponsored by ProSomnus Sleep Technologies.

RECRUITING
Registry status
NA
Development phase
49 participants
Enrollment target
2
Study locations

Study Summary

Title: Severe Label Expansion for EVO Positioner (SLEEP) Study Description: Single-arm study to determine the safety and effectiveness of treating severe obstructive sleep apnea using the EVO Sleep and Snore Device (ProSomnus Sleep Technologies, Pleasanton, CA). Objectives: To determine the safety and effectiveness of the EVO Sleep and Snore Device in individuals with severe obstructive sleep apnea. Endpoints: The primary effectiveness endpoint is the Sher criteria defined as a reduction of Apnea-Hypopnea Index (AHI) of at least 50% from the baseline value and a post-treatment AHI of less than 20 events/hour at 6 months following initiation of Oral Appliance Therapy (OAT) titration. AHI will be collected using HSAT at baseline and 6 months. The primary safety objective is to evaluate safety by summarizing all reported device and/or procedure related adverse events from the time the EVO device is introduced through 6 months. Study Population: A maximum of 49 individuals over the age of 18 years with severe obstructive sleep apnea will be enrolled. Description of Sites/Facilities Enrolling Participants: The study will be conducted at up to four sites, up to two of which could be located outside of the US. Description of Study Device: The study device is the EVO Sleep and Snore Device (ProSomnus Sleep Technologies, Pleasanton, CA). The device is a mandibular repositioning device used to treat obstructive sleep apnea. The device is currently cleared for the treatment of mild and moderate OSA. Study Duration: The time from when the study opens to enrollment until completion of data analyses is estimated to be 15 months.

Conditions Studied

Interventions

  • DEVICE EVO Sleep and Snore Device

Study Locations (2)

New York

  • Mount Sinai Integrative Sleep Center - New York

Texas

  • Star Sleep and Wellness - Dallas

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2025-08-01
Est. Completion 2026-12-31
Phase NA

Sponsor

ProSomnus Sleep Technologies

3 total trials

What the Registry Record Tells You About NCT07090395

The ClinicalTrials.gov registry entry for NCT07090395 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (78% lower). The listed sponsor is ProSomnus Sleep Technologies, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Obstructive Sleep Apnea appearing as the primary indexed condition, and to 1 intervention - of which EVO Sleep and Snore Device is the first listed.

NCT07090395 reports 2 study locations spanning 2 distinct geographic areas - top geographies include New York, Texas.

Frequently Asked Questions

What is clinical trial NCT07090395 about?

NCT07090395 is a clinical study titled "Severe Label Expansion for EVO Products Trial". Title: Severe Label Expansion for EVO Positioner (SLEEP) Study Description: Single-arm study to determine the safety and effectiveness of treating severe obstructive sleep apnea using the EVO Sleep and Snore Device (ProSomnus Sleep Technologies, Pleasanton, CA). Objectives: To determine the safety ...

What is the current status of trial NCT07090395?

This trial is currently recruiting. It is a NA study. The enrollment target is 49 participants. The study started on 2025-08-01. Estimated completion is 2026-12-31.

What conditions does trial NCT07090395 study?

This clinical trial studies the following conditions: Obstructive Sleep Apnea.

What interventions are being tested in trial NCT07090395?

The interventions under investigation include: EVO Sleep and Snore Device (DEVICE).

Who is sponsoring clinical trial NCT07090395?

This trial is sponsored by ProSomnus Sleep Technologies, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07090395 being conducted?

This trial has 2 study locations across New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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