Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04275362 · ClinicalTrials.gov registry record
Gait Analysis of a Lateral-Pivot Design Total Knee Replacement
A clinical trial of Knee Osteoarthritis, sponsored by More Foundation.
- Recruiting
- Registry status
- 102
- Enrollment target
- 1
- Study location
NCT04275362: Recruiting study of Knee Osteoarthritis, sponsored by More Foundation.
NCT04275362 is a study of Knee Osteoarthritis that is actively recruiting participants, run by More Foundation. The registered enrollment target is 102 participants, below the 303-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04275362, a study of Knee Osteoarthritis, is actively recruiting participants, sponsored by More Foundation.
- RECRUITING
- Registry status
- 102 participants
- Enrollment target
- 1
- Study location
Study Summary
Previous motion analysis studies have demonstrated excellent ability to distinguish subtle differences in gait between normal subjects and those suffering from arthritis. With proper techniques and analysis differences between osteoarthritis patient groups can be distinguished. Previous research has indicated that subjects who received a single-radius design total knee replacement have superior gait performance that those who received a multi-radius design total knee replacement. The DJO Global Empowr PS Knee System is a single-radius lateral pivot design. This design should achieve reproducible more natural knee function and improved patient outcomes and satisfaction. A motion analysis laboratory will be used to collect gait data from patients who are going to receive a Empowr PS knee device and also from age-matched control subjects. These data will be compared with data previously collected from patients who received Stryker Triathlon devices, Biomet Vanguard devices and age-matched healthy control subjects.
Primary Outcome
Compare maximum knee flexion angle in degrees during swing between healthy controls, and subjects with a dual pivot design total knee replacement (DJO Empowr), a single-radius (Triathlon, Stryker) knee replacement or a multi-radius (Vanguard, Zimmer Biomet) knee replacement.
Conditions Studied
Interventions
- DEVICE Control
- DEVICE DJO Empowr PS Knee System
- DEVICE Stryker Triathlon Total Knee System
- DEVICE Biomet Vanguard Complete Knee System
Study Locations (1)
Arizona
- MORE Foundation - Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 102 participants |
| Start Date | 2017-02-02 |
| Est. Completion | 2029-01-02 |
What NCT04275362 shows while recruiting
NCT04275362 is an observational study that tracks outcomes without assigning an intervention. The registered 102 participants enrollment target is mid-sized for trials with a published cap, below the 303-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (66% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 4 interventions - of which Control is the first listed.
NCT04275362 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT04275362 about?
NCT04275362 is a clinical study titled "Gait Analysis of a Lateral-Pivot Design Total Knee Replacement". Previous motion analysis studies have demonstrated excellent ability to distinguish subtle differences in gait between normal subjects and those suffering from arthritis. With proper techniques and analysis differences between osteoarthritis patient groups can be distinguished. Previous research has...
What is the current status of trial NCT04275362?
This trial is currently recruiting. The enrollment target is 102 participants. The study started on 2017-02-02. Estimated completion is 2029-01-02.
What conditions does trial NCT04275362 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT04275362?
The interventions under investigation include: Control (DEVICE), DJO Empowr PS Knee System (DEVICE), Stryker Triathlon Total Knee System (DEVICE), Biomet Vanguard Complete Knee System (DEVICE).
Who is sponsoring clinical trial NCT04275362?
This trial is sponsored by More Foundation, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04275362 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04275362's enrollment target sits among peer trials
102 41st of 101 higher than 61 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis
RECRUITING · NA
-
Focused Extracorporeal Shockwave Therapy for Knee Arthritis
RECRUITING · NA
-
A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression
RECRUITING · Early Phase 1
-
Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis
RECRUITING · Phase 4
-
Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis
RECRUITING
-
Mechanical Alignment Vs Kalipered Kinematic Alignment Total Knee Arthroplasty
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03704662 · 102 participants · NA
Preoperative Fractionated Radiation Therapy Versus Stereotactic Body Radiation Therapy for Resectable or Borderline Resectable, or Locally Advanced Type A Pancreatic Adenocarcinoma
- NCT04174742 · 102 participants
Self Reported Pain in Women While Undergoing Treatment for Non-metastatic Breast Cancer
- NCT04541082 · 102 participants · Phase 1
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
- NCT04563507 · 102 participants · Phase 2
Combined Immunotherapies in Metastatic ER+ Breast Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI