Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06245109 · ClinicalTrials.gov registry record · Phase 4
Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis
A Phase 4 study of Knee Osteoarthritis, sponsored by Northwestern University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 180
- Enrollment target
- 1
- Study location
NCT06245109 is a Phase 4 study of Knee Osteoarthritis that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 180 participants, below the 303-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06245109, a Phase 4 study of Knee Osteoarthritis, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 180 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a clinical trial of people who have pain due to knee osteoarthritis at Northwestern University Feinberg School of Medicine. The study will last for about 20 weeks. 180 qualified participants will be randomly assigned in a 1:1:1 ratio (60 participants per group) to one of three treatment groups: duloxetine, celecoxib, or placebo. Participants will have an Xray, knee MRI, brain MRI, blood draws, pain sensitivity testing, and asked to fill out questionnaires. The purpose of this study is to try to predict which participants will respond to the treatment.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Duloxetine
- DRUG Celecoxib
Study Locations (1)
Illinois
- Northwestern University - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2024-02-26 |
| Est. Completion | 2028-03-15 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06245109
The ClinicalTrials.gov registry entry for NCT06245109 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 303-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (41% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT06245109 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT06245109 about?
NCT06245109 is a clinical study titled "Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis". This is a clinical trial of people who have pain due to knee osteoarthritis at Northwestern University Feinberg School of Medicine. The study will last for about 20 weeks. 180 qualified participants will be randomly assigned in a 1:1:1 ratio (60 participants per group) to one of three treatment grou...
What is the current status of trial NCT06245109?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 180 participants. The study started on 2024-02-26. Estimated completion is 2028-03-15.
What conditions does trial NCT06245109 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT06245109?
The interventions under investigation include: Placebo (DRUG), Duloxetine (DRUG), Celecoxib (DRUG).
Who is sponsoring clinical trial NCT06245109?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06245109 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
RECRUITING · Phase 4
-
Extended Postoperative Oral Tranexamic Acid in Knee Replacement
ACTIVE NOT RECRUITING · Phase 4
-
The Efficacy of Diclofenac Gel for Breakthrough Pain and the Neuropathic Components of Pain in Knee Osteoarthritis
COMPLETED · Phase 4
-
The Effect of Intra-articular Bilateral Knee Injections of Zilretta on Performance Measures in Adults With Knee OA
COMPLETED · Phase 4
-
Efficacy of Celecoxib vs Placebo to Prevent Pain in a Paced Walk
COMPLETED · Phase 4
-
To Look at the Characteristics of Synovial Fluid and Cartilage Matrix in Osteoarthritic Knee After Hyaluronic Acid Injection
COMPLETED · Phase 4
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.