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NCT04023994 · ClinicalTrials.gov registry record · Phase 1

A Single Ascending Dose Study to Investigate the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Intravenously Administered RO7126209 in Healthy Participants

A Phase 1 study of Alzheimers Disease, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 1
Development phase
36
Enrollment target
1
Study location

NCT04023994 is a Phase 1 study of Alzheimers Disease that has completed, run by Hoffmann-La Roche. The registered enrollment target is 36 participants, below the 4,061-participant average among 142 other Alzheimers Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04023994, a Phase 1 study of Alzheimers Disease, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 1
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

Study BP41192 is a randomized, adaptive, placebo-controlled parallel group study to investigate the safety, tolerability, immunogenicity and pharmacokinetics of single-ascending intravenous (IV) doses of RO7126209 in healthy participants. RO7126209 is being developed for the treatment of Alzheimer's Disease.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG RO7126209

Study Locations (1)

North Carolina

  • PRA Health Sciences - Raleigh

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2019-08-03
Est. Completion 2020-07-17
Phase Phase 1

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT04023994

The ClinicalTrials.gov registry entry for NCT04023994 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,061-participant average among 142 other Alzheimers Disease trials with a reported enrollment target (99% lower). The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alzheimers Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04023994 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT04023994 about?

NCT04023994 is a clinical study titled "A Single Ascending Dose Study to Investigate the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Intravenously Administered RO7126209 in Healthy Participants". Study BP41192 is a randomized, adaptive, placebo-controlled parallel group study to investigate the safety, tolerability, immunogenicity and pharmacokinetics of single-ascending intravenous (IV) doses of RO7126209 in healthy participants. RO7126209 is being developed for the treatment of Alzheimer's...

What is the current status of trial NCT04023994?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2019-08-03. Estimated completion is 2020-07-17.

What conditions does trial NCT04023994 study?

This clinical trial studies the following conditions: Alzheimers Disease.

What interventions are being tested in trial NCT04023994?

The interventions under investigation include: Placebo (DRUG), RO7126209 (DRUG).

Who is sponsoring clinical trial NCT04023994?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04023994 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.