Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 4

EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)

NCT03950076 · View on ClinicalTrials.gov ↗

Study Summary

To assess whether edoxaban (60/30 mg daily) compared to non-antithrombotic medical therapy (either no antithrombotic therapy or antiplatelet monotherapy) reduces the risk of stroke (composite of ischemic, hemorrhagic and unspecified stroke) or systemic embolism in high-risk atrial fibrillation (CHA2DS2-VASc ≥2) patients with previous intracranial hemorrhage.

Interventions

  • DRUG Edoxaban
  • OTHER Non-anticoagulant medical therapy

Study Locations (20)

Other

  • Stat Research S.A. — Buenos Aires
  • Hospital Italiano de Buenos Aires — Buenos Aires
  • Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI) — Buenos Aires
  • Hospital Policial Churruca-Visca — Buenos Aires
  • Centro Instituto Neurologico Salta — Salta
  • Medical University of Innsbruck — Innsbruck
  • Institut für Akutneurologie und Stroke Unit (IANS), Landeskrankenhaus Feldkirch — Rankweil
  • Medical University of Vienna, Dept. of Neurology — Vienna
  • Salzkammergutklinikum Vöcklabruck — Vöcklabruck
  • Erasme Hospital — Brussels

Texas

  • The University of Texas at Austin, Dell Medical School — Austin
  • Texas Tech University Health Sciences Center at El Paso — El Paso
  • Baylor St. Luke's Medical Center — Houston

Illinois

  • Alexian Brothers Medical Center — Elk Grove Village
  • Presence Care Transformation Corporation — Lisle

Pennsylvania

  • The Hospital of the University of Pennsylvania — Philadelphia
  • Allegheny General Hospital — Pittsburgh

Louisiana

  • Tulane University Medical Center — New Orleans

New York

  • New York Presbyterian - Queens — Queens

Washington

  • MultiCare Institute for Research & Innovation — Tacoma

Trial Details

FieldValue
Enrollment Target 948 participants
Start Date 2019-09-20
Est. Completion 2026-05-13
Phase Phase 4

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03950076

The ClinicalTrials.gov registry entry for NCT03950076 describes a study currently listed as active not recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 948 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Population Health Research Institute, which has 68 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Atrial Fibrillation appearing as the primary indexed condition, and to 2 interventions — of which Edoxaban is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03950076 reports 20 study locations spanning 7 distinct geographic areas — top geographies include Other, Texas, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03950076 about?

NCT03950076 is a clinical study titled "EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)". To assess whether edoxaban (60/30 mg daily) compared to non-antithrombotic medical therapy (either no antithrombotic therapy or antiplatelet monotherapy) reduces the risk of stroke (composite of ischemic, hemorrhagic and unspecified stroke) or systemic embolism in high-risk atrial fibrillation (CHA2...

What is the current status of trial NCT03950076?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 948 participants. The study started on 2019-09-20. Estimated completion is 2026-05-13.

What conditions does trial NCT03950076 study?

This clinical trial studies the following conditions: Atrial Fibrillation, Intracranial Hemorrhages. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03950076?

The interventions under investigation include: Edoxaban (DRUG), Non-anticoagulant medical therapy (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03950076?

This trial is sponsored by Population Health Research Institute, which has 68 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03950076 being conducted?

This trial has 20 study locations across Illinois, Louisiana, New York, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial