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NCT03603912 · ClinicalTrials.gov registry record · Phase 4

Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)

A Phase 4 study of Atrial Fibrillation, sponsored by Mina Chung, MD.

Active
Registry status
Phase 4
Development phase
175
Enrollment target
1
Study location

NCT03603912 is a Phase 4 study of Atrial Fibrillation that is active but no longer recruiting, run by Mina Chung, MD. The registered enrollment target is 175 participants, below the 2,996-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03603912, a Phase 4 study of Atrial Fibrillation, is active but no longer recruiting, sponsored by Mina Chung, MD.

ACTIVE NOT RECRUITING
Registry status
Phase 4
Development phase
175 participants
Enrollment target
1
Study location

Study Summary

Prospective randomized open-label blinded endpoint (PROBE) 2x2 factorial study of metformin extended release up to 750 mg BID and lifestyle and risk factor modification (LRFM) in CIED patients with at least 1 ≥5 minute episode of AF over the prior 3 months. Randomization will be stratified by pacemaker vs. ICD and rhythm at enrollment (sinus rhythm/atrial paced vs. AF).

Conditions Studied

Atrial Fibrillation

Interventions

  • DRUG Metformin
  • BEHAVIORAL Lifestyle/Risk Factor Modification

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 175 participants
Start Date 2018-08-24
Est. Completion 2026-12
Phase Phase 4

Sponsor

Mina Chung, MD

1 total trials

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What the Registry Record Tells You About NCT03603912

The ClinicalTrials.gov registry entry for NCT03603912 describes a study currently listed as active not recruiting, categorized as Phase 4. The registered enrollment target is 175 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,996-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (94% lower). The listed sponsor is Mina Chung, MD, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Atrial Fibrillation appearing as the primary indexed condition, and to 2 interventions - of which Metformin is the first listed.

NCT03603912 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT03603912 about?

NCT03603912 is a clinical study titled "Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)". Prospective randomized open-label blinded endpoint (PROBE) 2x2 factorial study of metformin extended release up to 750 mg BID and lifestyle and risk factor modification (LRFM) in CIED patients with at least 1 ≥5 minute episode of AF over the prior 3 months. Randomization will be stratified by pacema...

What is the current status of trial NCT03603912?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 175 participants. The study started on 2018-08-24. Estimated completion is 2026-12.

What conditions does trial NCT03603912 study?

This clinical trial studies the following conditions: Atrial Fibrillation.

What interventions are being tested in trial NCT03603912?

The interventions under investigation include: Metformin (DRUG), Lifestyle/Risk Factor Modification (BEHAVIORAL).

Who is sponsoring clinical trial NCT03603912?

This trial is sponsored by Mina Chung, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03603912 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.