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ClinicalTrials.gov 19 recruiting now full pipeline

Stage III Prostate Cancer AJCC v8: full-pipeline trial registry

19 of 29 indexed Stage III Prostate Cancer AJCC v8 trials are currently recruiting.

Corpus placement: #552 of 28,707 conditions by registered trial count.

29 US clinical trials · 19 currently recruiting · #552 of 28,707 conditions by registered trial count

Stage III Prostate Cancer AJCC v8: 29 US clinical trials tracked, 19 recruiting.

Stage III Prostate Cancer AJCC v8 is the subject of 29 registered US clinical trials on ClinicalTrials.gov, 19 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Mayo Clinic, running 6 of these trials.

Enrollment posture brief

Registry condition stage-iii-prostate-cancer-ajcc-v8

OPEN 19 | RECR 66% | LATE 7 | EARLY 10 | RANK #552 | SPON 6

Nearest open-share peer: Hematopoietic and Lymphoid System Neoplasm (66% recruiting · 32 trials)

Stage III Prostate Cance (th…66%Advanced Breast Cancer62.1%Amyloidosis51.7%Arthritis, Rheumatoid17.2%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Stage III Prostate Cancer AJCC v8

Stage III Prostate Cancer AJCC v8 lists 19 open slots (66% of 29 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage III Prostate Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage III Prostate Cancer AJCC v8 is recruiting above its size-band peers.

    19 of 29 indexed trials (65.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage III Prostate Cancer AJCC v8 research.

    Mayo Clinic accounts for 6 of 29 trials (20.7%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Typical Stage III Prostate Cancer AJCC v8 enrolment sits around 80 participants.

    Median target enrolment is 80 among the 29 trials that report a genuine target (sentinel values excluded). 16 of those (55.2%) plan for fewer than 100 participants.

  4. Stage III Prostate Cancer AJCC v8 research is mostly interventional.

    28 interventional and 1 observational studies make up this index (96.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 28Phase 37

Open and recent trials

29 total, page 1 of 1

RECRUITING Phase 3 1,209 participants

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

NRG Oncology

NCT05946213

RECRUITING Phase 3 586 participants

Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial

NRG Oncology

NCT04134260

RECRUITING Phase 3 240 participants

Vitamin D for Prostate Endocrine Therapy

University of Rochester

NCT05838716

RECRUITING Phase 2 210 participants

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

City of Hope Medical Center

NCT05869682

RECRUITING Phase 2 200 participants

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

M.D. Anderson Cancer Center

NCT04947254

RECRUITING NA 186 participants

Image-Guidance and Online Adaptation With Stereotactic Body Radiation Therapy for the Treatment of Localized Prostate Cancer, MANTICORE Trial

Jonsson Comprehensive Cancer Center

NCT07276438

RECRUITING NA 144 participants

Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer

Mayo Clinic

NCT06325046

RECRUITING NA 120 participants

Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

Thomas Jefferson University

NCT05487846

RECRUITING Phase 3 118 participants

SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

Mayo Clinic

NCT06205316

RECRUITING NA 80 participants

Computed Tomography-Guided Stereotactic Body Radiation Therapy With Intrafraction Motion Monitoring for the Treatment of Localized Prostate Cancer, ILLUSION Trial

Jonsson Comprehensive Cancer Center

NCT06995053

RECRUITING Phase 2 75 participants

Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer

University of California, Davis

NCT06173362

RECRUITING Phase 3 72 participants

REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial

Emory University

NCT06650579

RECRUITING NA 52 participants

High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma

Jonsson Comprehensive Cancer Center

NCT04945642

RECRUITING NA 50 participants

Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer

Mayo Clinic

NCT06389786

RECRUITING Phase 2 38 participants

Evaluating In Home Cancer Therapy Versus In Clinic Cancer Therapy in Black Men With Locally Advanced, Biochemically Recurrent and Metastatic Prostate Cancer

Mayo Clinic

NCT07073794

RECRUITING NA 30 participants

Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer

Emory University

NCT04725903

RECRUITING Phase 2 30 participants

Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial

Mayo Clinic

NCT07025369

RECRUITING NA 25 participants

Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy

Mayo Clinic

NCT06940271

RECRUITING NA 20 participants

Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors

University of Southern California

NCT06500169

ACTIVE NOT RECRUITING Phase 3 2,753 participants

Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial

NRG Oncology

NCT04513717

ACTIVE NOT RECRUITING 200 participants

Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners

M.D. Anderson Cancer Center

NCT04189770

ACTIVE NOT RECRUITING Phase 3 186 participants

Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer

M.D. Anderson Cancer Center

NCT03987386

ACTIVE NOT RECRUITING Phase 2 141 participants

An Investigational Scan (68Ga-PSMA-11 PET) for the Imaging of Prostate Cancer

University of Washington

NCT04777071

ACTIVE NOT RECRUITING Phase 2 94 participants

RElugolix VErsus LeUprolide Cardiac Trial

Emory University

NCT05320406

ACTIVE NOT RECRUITING NA 64 participants

Watchful Living in Improving Quality of Life in Participants With Localized Prostate Cancer on Active Surveillance and Their Partners

M.D. Anderson Cancer Center

NCT03575832

ACTIVE NOT RECRUITING Phase 1 15 participants

Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate

Jonsson Comprehensive Cancer Center

NCT03582475

ACTIVE NOT RECRUITING Phase 2 12 participants

Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery

Roswell Park Cancer Institute

NCT03899987

ACTIVE NOT RECRUITING NA 6 participants

Lifestyle Intervention for the Reduction of Prostate Cancer Disparities Among African Americans

M.D. Anderson Cancer Center

NCT04215029

COMPLETED Phase 1 22 participants

Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of Recurring

NRG Oncology

NCT04037254

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 8
Phase 3 7

Named interventions

Most-linked intervention names on Stage III Prostate Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
12 trials
Computed Tomography Procedure
8 trials
Questionnaire Administration Other
5 trials
Bone Scan Procedure
5 trials
Magnetic Resonance Imaging Procedure
5 trials
Quality-of-Life Assessment Other
5 trials
Survey Administration Other
4 trials
Apalutamide Drug
3 trials

US sites by state

Facility locations filed on Stage III Prostate Cancer AJCC v8 trials. A trial with sites in several states counts in each.

California 11 trials
Texas 5 trials
Arizona 5 trials
Georgia 4 trials
Minnesota 3 trials
Florida 3 trials
Arkansas 3 trials
Wisconsin 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage III Prostate Cancer AJCC v8 page

29 registered trials, 19 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 19 Stage III Prostate Cancer AJCC v8 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Mayo Clinic sponsors the most Stage III Prostate Cancer AJCC v8 trials on record, review their full trial history before evaluating a specific study. See Mayo Clinic's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage III Prostate Cancer AJCC v8 condition card totals 29 registered trials; most-linked intervention Biospecimen Collection; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.