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2026 data Public-data reference. official source

Stage IIC Prostate Cancer AJCC v8

Open-data reference.

16 US clinical trials · 5 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 200 participants

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

M.D. Anderson Cancer Center

NCT04947254

RECRUITING Phase 3 118 participants

SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma

Mayo Clinic

NCT06205316

RECRUITING Phase 2 70 participants

Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer

Ohio State University Comprehensive Cancer Center

NCT06330805

RECRUITING NA 52 participants

High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma

Jonsson Comprehensive Cancer Center

NCT04945642

RECRUITING Phase 2 30 participants

Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial

Mayo Clinic

NCT07025369

ACTIVE NOT RECRUITING NA 208 participants

Germline DNA-Based Radiosensitivity Biomarker Influence on Toxicity Following Prostate Radiotherapy, GARUDA Trial

Jonsson Comprehensive Cancer Center

NCT04624256

ACTIVE NOT RECRUITING 200 participants

Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners

M.D. Anderson Cancer Center

NCT04189770

ACTIVE NOT RECRUITING Phase 2 141 participants

An Investigational Scan (68Ga-PSMA-11 PET) for the Imaging of Prostate Cancer

University of Washington

NCT04777071

ACTIVE NOT RECRUITING Phase 2 133 participants

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

City of Hope Medical Center

NCT04519879

ACTIVE NOT RECRUITING Phase 2 94 participants

RElugolix VErsus LeUprolide Cardiac Trial

Emory University

NCT05320406

ACTIVE NOT RECRUITING NA 64 participants

Watchful Living in Improving Quality of Life in Participants With Localized Prostate Cancer on Active Surveillance and Their Partners

M.D. Anderson Cancer Center

NCT03575832

ACTIVE NOT RECRUITING Phase 2 14 participants

Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer

Rutgers, The State University of New Jersey

NCT04253483

ACTIVE NOT RECRUITING NA 12 participants

Neoadjuvant Dietary Intervention in Intermediate Risk Prostate Cancer

M.D. Anderson Cancer Center

NCT04985565

ACTIVE NOT RECRUITING Phase 2 12 participants

Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery

Roswell Park Cancer Institute

NCT03899987

ACTIVE NOT RECRUITING NA 6 participants

Lifestyle Intervention for the Reduction of Prostate Cancer Disparities Among African Americans

M.D. Anderson Cancer Center

NCT04215029

COMPLETED Phase 1 22 participants

Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of Recurring

NRG Oncology

NCT04037254

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 8
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Stage IIC Prostate Cancer AJCC v8 Trial Landscape

ClinicalTrials.gov lists 16 US studies indexed under Stage IIC Prostate Cancer AJCC v8, and 5 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Stage IIC Prostate Cancer AJCC v8 shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Stage IIC Prostate Cancer AJCC v8 is led by M.D. Anderson Cancer Center with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Stage IIC Prostate Cancer AJCC v8?

PlainTrial tracks 16 US clinical trials for Stage IIC Prostate Cancer AJCC v8, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stage IIC Prostate Cancer AJCC v8?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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