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NCT07258511 · ClinicalTrials.gov registry record · Phase 3

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

A Phase 3 study of Multiple Myeloma, sponsored by Janssen Research & Development.

Recruiting
Registry status
Phase 3
Development phase
400
Enrollment target
20
Study locations

NCT07258511 is a Phase 3 study of Multiple Myeloma that is actively recruiting participants, run by Janssen Research & Development. The registered enrollment target is 400 participants, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (27% lower). The trial reports 20 study locations across 10 states.

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The verdict

NCT07258511, a Phase 3 study of Multiple Myeloma, is actively recruiting participants, sponsored by Janssen Research & Development.

RECRUITING
Registry status
Phase 3
Development phase
400 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to evaluate how well JNJ-79635322 works when compared with an anti-B-cell maturation antigen (BCMA)xCD3 bispecific antibody.

Conditions Studied

Interventions

  • DRUG Teclistamab
  • DRUG JNJ-79635322

Study Locations (20)

Other

  • Box Hill Hospital - Box Hill
  • Mater Misericordiae Ltd - Brisbane
  • St Vincents Hospital Melbourne - Fitzroy
  • The Alfred Hospital - Melbourne
  • Gold Coast University Hospital - Southport
  • Hospital De Clinicas De Porto Alegre - Porto Alegre
  • Soroka Medical Center - Beersheba
  • Bnai Zion Medical Center - Haifa

New York

  • Mount Sinai Chelsea - New York
  • Icahn School of Medicine at Mount Sinai - New York
  • Memorial Sloan Kettering Cancer Center - New York

Connecticut

  • University of Connecticut Health Center - Farmington
  • Yale Cancer Center - New Haven

California

  • USC Norris Comprehensive Cancer Center - Los Angeles

Florida

  • Florida Cancer Specialists & Research Institute - Fort Myers

Georgia

  • Emory University - Atlanta

Kentucky

  • Norton Cancer Institute - Louisville

North Carolina

  • Durham VAMC - Durham

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2026-02-04
Est. Completion 2031-09-30
Phase Phase 3

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT07258511

The ClinicalTrials.gov registry entry for NCT07258511 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (27% lower). The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 2 interventions - of which Teclistamab is the first listed.

NCT07258511 reports 20 study locations spanning 10 distinct geographic areas - top geographies include Other, New York, Connecticut.

Frequently Asked Questions

What is clinical trial NCT07258511 about?

NCT07258511 is a clinical study titled "A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma". The purpose of this study is to evaluate how well JNJ-79635322 works when compared with an anti-B-cell maturation antigen (BCMA)xCD3 bispecific antibody.

What is the current status of trial NCT07258511?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 400 participants. The study started on 2026-02-04. Estimated completion is 2031-09-30.

What conditions does trial NCT07258511 study?

This clinical trial studies the following conditions: Multiple Myeloma.

What interventions are being tested in trial NCT07258511?

The interventions under investigation include: Teclistamab (DRUG), JNJ-79635322 (DRUG).

Who is sponsoring clinical trial NCT07258511?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07258511 being conducted?

This trial has 20 study locations across California, Connecticut, Florida, Georgia, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.