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NCT03534934 · ClinicalTrials.gov registry record · NA
CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD
A NA study of Osteoporosis and Pulmonary Disease, Chronic Obstructive, sponsored by Punam K Saha.
- Completed
- Registry status
- NA
- Development phase
- 560
- Enrollment target
- 2
- Study locations
NCT03534934: Completed NA study of Osteoporosis and Pulmonary Disease, Chronic Obstructive, sponsored by Punam K Saha.
NCT03534934 is a NA study of Osteoporosis and Pulmonary Disease, Chronic Obstructive that has completed, run by Punam K Saha. The registered enrollment target is 560 participants, below the 1,539-participant average among 84 other Osteoporosis trials with a reported enrollment target (64% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03534934, a NA study of Osteoporosis and Pulmonary Disease, Chronic Obstructive, has completed, sponsored by Punam K Saha.
- COMPLETED
- Registry status
- NA
- Development phase
- 560 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this translational study is to establish a newly emerging CT-based tool for the characterization of changes in bone micro-architecture and assessment of their implications for fracture-risk in a population of COPD patients at risk for osteoporosis. The tool will be suitable and generalizable across emerging CT scanners from different vendors, and it will provide a more structurally-based assessment of osteoporosis and bone loss than is provided by simple bone density measures. The study will characterize the impact of different COPD-related factors on bone structure, and their implications for fracture-risk, leading to the development of a COPD-specific model for assessment of fracture-risk that will utilize patient-specific demographic, clinical and radiographic data, and CT BMD at the spine, as well as bone structural measures at the hip and/or ankle.
Primary Outcome
Method: Prevalent fracture cases at the baseline visit will be determined using expert visual reading of the baseline lateral spine CT scout scan.
Conditions Studied
Interventions
- OTHER Questionnaires
- DIAGNOSTIC_TEST Blood Test
- DIAGNOSTIC_TEST Vital signs
- DIAGNOSTIC_TEST Urine Pregnancy Test
- DIAGNOSTIC_TEST Duel-energy X-ray absorptiometry scan
Study Locations (2)
Iowa
- University of Iowa Hospitals and Clinics - Iowa City
New York
- Columbia University Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 560 participants |
| Start Date | 2019-02-26 |
| Est. Completion | 2025-03-19 |
| Phase | NA |
What the finished NCT03534934 record still lists
NCT03534934 is an interventional study that assigns participants to a tested intervention. The registered 560 participants enrollment target is mid-sized for trials with a published cap, below the 1,539-participant average among 84 other Osteoporosis trials with a reported enrollment target (64% lower).
The record links to 2 conditions, with Osteoporosis appearing as the primary indexed condition, and to 5 interventions - of which Questionnaires is the first listed.
NCT03534934 reports a single indexed study location in Iowa, New York.
Frequently Asked Questions
What is clinical trial NCT03534934 about?
NCT03534934 is a clinical study titled "CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD". The goal of this translational study is to establish a newly emerging CT-based tool for the characterization of changes in bone micro-architecture and assessment of their implications for fracture-risk in a population of COPD patients at risk for osteoporosis. The tool will be suitable and generaliz...
What is the current status of trial NCT03534934?
This trial is currently completed. It is a NA study. The enrollment target is 560 participants. The study started on 2019-02-26. Estimated completion is 2025-03-19.
What conditions does trial NCT03534934 study?
This clinical trial studies the following conditions: Osteoporosis, Pulmonary Disease, Chronic Obstructive.
What interventions are being tested in trial NCT03534934?
The interventions under investigation include: Questionnaires (OTHER), Blood Test (DIAGNOSTIC_TEST), Vital signs (DIAGNOSTIC_TEST), Urine Pregnancy Test (DIAGNOSTIC_TEST), Duel-energy X-ray absorptiometry scan (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03534934?
This trial is sponsored by Punam K Saha, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03534934 being conducted?
This trial has 2 study locations across Iowa, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoporosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03534934's enrollment target sits among peer trials
560 17th of 84 higher than 67 of 84 other Osteoporosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoporosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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