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NCT03419858 · ClinicalTrials.gov registry record · Early Phase 1

The Role of Opioidergic Systems in Breathing Based Analgesia

A Early Phase 1 study of Pain, sponsored by University of California, San Diego.

Completed
Registry status
Early Phase 1
Development phase
60
Enrollment target
1
Study location

NCT03419858 is a Early Phase 1 study of Pain that has completed, run by University of California, San Diego. The registered enrollment target is 60 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03419858, a Early Phase 1 study of Pain, has completed, sponsored by University of California, San Diego.

COMPLETED
Registry status
Early Phase 1
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The purpose of this psychophysical and pharmacologic study is to determine if slow-breathing induced pain relief is mediated by endogenous opioids in response to intravenous (IV) administration of the opioid antagonist naloxone during noxious heat stimulation. We were also interested in disentangling the endogenous analgesic mechanisms supporting mindfulness-based analgesia.

Conditions Studied

Pain

Interventions

  • OTHER Saline
  • DRUG Naloxone
  • BEHAVIORAL Mindfulness Meditation
  • BEHAVIORAL Placebo Meditation
  • BEHAVIORAL Slow-Breathing

Study Locations (1)

North Carolina

  • Wake Forest University Health Sciences - Winston-Salem

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2017-03-13
Est. Completion 2017-06-27
Phase Early Phase 1

Sponsor

University of California, San Diego

775 total trials

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What the Registry Record Tells You About NCT03419858

The ClinicalTrials.gov registry entry for NCT03419858 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 304-participant average among 374 other Pain trials with a reported enrollment target (80% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 5 interventions - of which Saline is the first listed.

NCT03419858 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT03419858 about?

NCT03419858 is a clinical study titled "The Role of Opioidergic Systems in Breathing Based Analgesia". The purpose of this psychophysical and pharmacologic study is to determine if slow-breathing induced pain relief is mediated by endogenous opioids in response to intravenous (IV) administration of the opioid antagonist naloxone during noxious heat stimulation. We were also interested in disentanglin...

What is the current status of trial NCT03419858?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 60 participants. The study started on 2017-03-13. Estimated completion is 2017-06-27.

What conditions does trial NCT03419858 study?

This clinical trial studies the following conditions: Pain.

What interventions are being tested in trial NCT03419858?

The interventions under investigation include: Saline (OTHER), Naloxone (DRUG), Mindfulness Meditation (BEHAVIORAL), Placebo Meditation (BEHAVIORAL), Slow-Breathing (BEHAVIORAL).

Who is sponsoring clinical trial NCT03419858?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03419858 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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