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NCT03243942 · ClinicalTrials.gov registry record · Phase 2
Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement
A Phase 2 study of Heart Failure and Blood Pressure, sponsored by Thomas Jefferson University.
- Completed
- Registry status
- Phase 2
- Development phase
- 56
- Enrollment target
- 1
- Study location
NCT03243942 is a Phase 2 study of Heart Failure and Blood Pressure that has completed, run by Thomas Jefferson University. The registered enrollment target is 56 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03243942, a Phase 2 study of Heart Failure and Blood Pressure, has completed, sponsored by Thomas Jefferson University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
The fundamental hypothesis of this project is that real-time intracardiac pressures can be monitored and quantified noninvasively in humans using a novel contrast-enhanced ultrasound technique called subharmonic-aided pressure estimation (SHAPE).This study will use contrast echocardiography to assess the accuracy of SHAPE compared to simultaneously acquired intracardiac pressures measured invasively during cardiac catheterization. This study is designed to verify that contrast echocardiography using the SHAPE method, already proven in a canine model and tested in a human pilot study can be used as a surrogate for cardiac catheterization with sufficient accuracy to allow clinical applicability in humans.
Conditions Studied
Interventions
- DRUG Definity
Study Locations (1)
Pennsylvania
- Thomas Jefferson University and Thomas Jefferson University Hospital - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2017-06-01 |
| Est. Completion | 2019-06-26 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03243942
The ClinicalTrials.gov registry entry for NCT03243942 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (97% lower). The listed sponsor is Thomas Jefferson University, which has 292 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Definity is the first listed.
NCT03243942 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03243942 about?
NCT03243942 is a clinical study titled "Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement". The fundamental hypothesis of this project is that real-time intracardiac pressures can be monitored and quantified noninvasively in humans using a novel contrast-enhanced ultrasound technique called subharmonic-aided pressure estimation (SHAPE).This study will use contrast echocardiography to asses...
What is the current status of trial NCT03243942?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 56 participants. The study started on 2017-06-01. Estimated completion is 2019-06-26.
What conditions does trial NCT03243942 study?
This clinical trial studies the following conditions: Heart Failure, Blood Pressure, Cardiac Catheterization, Echocardiography, Heart Ventricles.
What interventions are being tested in trial NCT03243942?
The interventions under investigation include: Definity (DRUG).
Who is sponsoring clinical trial NCT03243942?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03243942 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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