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NCT03243942 · ClinicalTrials.gov registry record · Phase 2
Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement
A Phase 2 study of Heart Failure and Blood Pressure, sponsored by Thomas Jefferson University.
- Completed
- Registry status
- Phase 2
- Development phase
- 56
- Enrollment target
- 1
- Study location
NCT03243942: Completed Phase 2 study of Heart Failure and Blood Pressure, sponsored by Thomas Jefferson University.
NCT03243942 is a Phase 2 study of Heart Failure and Blood Pressure that has completed, run by Thomas Jefferson University. The registered enrollment target is 56 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03243942, a Phase 2 study of Heart Failure and Blood Pressure, has completed, sponsored by Thomas Jefferson University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
The fundamental hypothesis of this project is that real-time intracardiac pressures can be monitored and quantified noninvasively in humans using a novel contrast-enhanced ultrasound technique called subharmonic-aided pressure estimation (SHAPE).This study will use contrast echocardiography to assess the accuracy of SHAPE compared to simultaneously acquired intracardiac pressures measured invasively during cardiac catheterization. This study is designed to verify that contrast echocardiography using the SHAPE method, already proven in a canine model and tested in a human pilot study can be used as a surrogate for cardiac catheterization with sufficient accuracy to allow clinical applicability in humans.
Primary Outcome
Correlation
Conditions Studied
Interventions
- DRUG Definity
Study Locations (1)
Pennsylvania
- Thomas Jefferson University and Thomas Jefferson University Hospital - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2017-06-01 |
| Est. Completion | 2019-06-26 |
| Phase | Phase 2 |
What the finished NCT03243942 record still lists
NCT03243942 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (97% lower).
The record links to 5 conditions, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Definity is the first listed.
NCT03243942 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03243942 about?
NCT03243942 is a clinical study titled "Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement". The fundamental hypothesis of this project is that real-time intracardiac pressures can be monitored and quantified noninvasively in humans using a novel contrast-enhanced ultrasound technique called subharmonic-aided pressure estimation (SHAPE).This study will use contrast echocardiography to asses...
What is the current status of trial NCT03243942?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 56 participants. The study started on 2017-06-01. Estimated completion is 2019-06-26.
What conditions does trial NCT03243942 study?
This clinical trial studies the following conditions: Heart Failure, Blood Pressure, Cardiac Catheterization, Echocardiography, Heart Ventricles.
What interventions are being tested in trial NCT03243942?
The interventions under investigation include: Definity (DRUG).
Who is sponsoring clinical trial NCT03243942?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03243942 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03243942's enrollment target sits among peer trials
56 271st of 397 higher than 126 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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