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NCT03238300 · ClinicalTrials.gov registry record · Phase 2
Neuroscience-Informed Treatment Development for Adolescent Alcohol Use
A Phase 2 study of Alcohol Drinking and Control, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Phase 2
- Development phase
- 57
- Enrollment target
- 1
- Study location
NCT03238300: Completed Phase 2 study of Alcohol Drinking and Control, sponsored by Medical University of South Carolina.
NCT03238300 is a Phase 2 study of Alcohol Drinking and Control that has completed, run by Medical University of South Carolina. The registered enrollment target is 57 participants, below the 630-participant average among 85 other Alcohol Drinking trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03238300, a Phase 2 study of Alcohol Drinking and Control, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 57 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement, on brains of youth (ages 15-19) using magnetic resonance imaging (MRI).
Primary Outcome
Using magnetic resonance spectroscopy and a within-subjects design, we will determine the effect of N-Acetylcysteine versus placebo on modulating anterior cingulate glutamate levels in adolescents. Values provided are absolute values (mmol/kg) at the end of each intervention period. Due to complexities of this method, "normal" levels of glutamate are not known; thus, we cannot make conclusions about the meaning of "higher" or "lower" glutamate levels when comparing N-acetylcysteine to placebo.
Conditions Studied
Interventions
- DRUG Placebo Oral Capsule
- DRUG N-Acetylcysteine
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 57 participants |
| Start Date | 2017-10-16 |
| Est. Completion | 2022-03-01 |
| Phase | Phase 2 |
What the finished NCT03238300 record still lists
NCT03238300 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 57 participants, a relatively small participant target, below the 630-participant average among 85 other Alcohol Drinking trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Alcohol Drinking appearing as the primary indexed condition, and to 2 interventions - of which Placebo Oral Capsule is the first listed.
NCT03238300 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT03238300 about?
NCT03238300 is a clinical study titled "Neuroscience-Informed Treatment Development for Adolescent Alcohol Use". This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement, on brains of youth (ages 15-19) using magnetic resonance imaging (MRI).
What is the current status of trial NCT03238300?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 57 participants. The study started on 2017-10-16. Estimated completion is 2022-03-01.
What conditions does trial NCT03238300 study?
This clinical trial studies the following conditions: Alcohol Drinking, Control.
What interventions are being tested in trial NCT03238300?
The interventions under investigation include: Placebo Oral Capsule (DRUG), N-Acetylcysteine (DRUG).
Who is sponsoring clinical trial NCT03238300?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03238300 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Drinking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03238300's enrollment target sits among peer trials
57 67th of 85 higher than 19 of 85 other Alcohol Drinking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Drinking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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