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NCT07404852 · ClinicalTrials.gov registry record · NA
Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke
A NA study of Acute Ischemic Stroke and Large Vessel Occlusion, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 65
- Enrollment target
- 1
- Study location
NCT07404852 is a NA study of Acute Ischemic Stroke and Large Vessel Occlusion that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 65 participants, below the 349-participant average among 25 other Acute Ischemic Stroke trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07404852, a NA study of Acute Ischemic Stroke and Large Vessel Occlusion, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 65 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a randomized open-label, with blinded outcome pilot study to evaluate the effect on inflammatory and brain injury laboratory values and explore clinical outcomes in patients who present with ischemic strokes due to large vessel occlusions and are treated with either current accepted management, or accepted management in addition to transcutaneous auricular vagal nerve stimulation.
Conditions Studied
Interventions
- DEVICE transcutaneous auricular vagal nerve stimulation
- DEVICE Sham transcutaneous vagal nerve stimulation
Study Locations (1)
Missouri
- Barnes-Jewish Hospital - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2026-02-23 |
| Est. Completion | 2028-02-29 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07404852
The ClinicalTrials.gov registry entry for NCT07404852 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 65 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 349-participant average among 25 other Acute Ischemic Stroke trials with a reported enrollment target (81% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Acute Ischemic Stroke appearing as the primary indexed condition, and to 2 interventions - of which transcutaneous auricular vagal nerve stimulation is the first listed.
NCT07404852 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT07404852 about?
NCT07404852 is a clinical study titled "Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke". This is a randomized open-label, with blinded outcome pilot study to evaluate the effect on inflammatory and brain injury laboratory values and explore clinical outcomes in patients who present with ischemic strokes due to large vessel occlusions and are treated with either current accepted manageme...
What is the current status of trial NCT07404852?
This trial is currently recruiting. It is a NA study. The enrollment target is 65 participants. The study started on 2026-02-23. Estimated completion is 2028-02-29.
What conditions does trial NCT07404852 study?
This clinical trial studies the following conditions: Acute Ischemic Stroke, Large Vessel Occlusion.
What interventions are being tested in trial NCT07404852?
The interventions under investigation include: transcutaneous auricular vagal nerve stimulation (DEVICE), Sham transcutaneous vagal nerve stimulation (DEVICE).
Who is sponsoring clinical trial NCT07404852?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07404852 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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