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NCT04676802 · ClinicalTrials.gov registry record · Phase 2

Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone

A Phase 2 study of Pain, Postoperative and Osteoarthritis Thumb, sponsored by Stanford University.

Recruiting
Registry status
Phase 2
Development phase
121
Enrollment target
2
Study locations

NCT04676802 is a Phase 2 study of Pain, Postoperative and Osteoarthritis Thumb that is actively recruiting participants, run by Stanford University. The registered enrollment target is 121 participants, below the 272-participant average among 108 other Pain, Postoperative trials with a reported enrollment target (56% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT04676802, a Phase 2 study of Pain, Postoperative and Osteoarthritis Thumb, is actively recruiting participants, sponsored by Stanford University.

RECRUITING
Registry status
Phase 2
Development phase
121 participants
Enrollment target
2
Study locations

Study Summary

In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the efficacy of a combination of non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine analogue substance (oxycodone) for pain management in the first 30 days after surgery.

Interventions

  • DRUG NSAID capsules
  • DRUG Opioid capsule

Study Locations (2)

California

  • Stanford Health Care - Redwood City

Utah

  • University of Utah Health Care - Salt Lake City

Trial Details

FieldValue
Enrollment Target 121 participants
Start Date 2021-12-27
Est. Completion 2027-08
Phase Phase 2

Sponsor

Stanford University

1,744 total trials

What the Registry Record Tells You About NCT04676802

The ClinicalTrials.gov registry entry for NCT04676802 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 121 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 272-participant average among 108 other Pain, Postoperative trials with a reported enrollment target (56% lower). The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 2 interventions - of which NSAID capsules is the first listed.

NCT04676802 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Utah.

Frequently Asked Questions

What is clinical trial NCT04676802 about?

NCT04676802 is a clinical study titled "Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone". In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce ...

What is the current status of trial NCT04676802?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 121 participants. The study started on 2021-12-27. Estimated completion is 2027-08.

What conditions does trial NCT04676802 study?

This clinical trial studies the following conditions: Pain, Postoperative, Osteoarthritis Thumb.

What interventions are being tested in trial NCT04676802?

The interventions under investigation include: NSAID capsules (DRUG), Opioid capsule (DRUG).

Who is sponsoring clinical trial NCT04676802?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04676802 being conducted?

This trial has 2 study locations across California, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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