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NCT04676802 · ClinicalTrials.gov registry record · Phase 2
Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
A Phase 2 study of Pain, Postoperative and Osteoarthritis Thumb, sponsored by Stanford University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 121
- Enrollment target
- 2
- Study locations
NCT04676802: Recruiting Phase 2 study of Pain, Postoperative and Osteoarthritis Thumb, sponsored by Stanford University.
NCT04676802 is a Phase 2 study of Pain, Postoperative and Osteoarthritis Thumb that is actively recruiting participants, run by Stanford University. The registered enrollment target is 121 participants, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (56% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04676802, a Phase 2 study of Pain, Postoperative and Osteoarthritis Thumb, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 121 participants
- Enrollment target
- 2
- Study locations
Study Summary
In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the efficacy of a combination of non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine analogue substance (oxycodone) for pain management in the first 30 days after surgery.
Primary Outcome
The number of capsules consumed in the last 24 hours. Consumption rate and overall consumption will be compared between groups to assess efficacy and inform further statistical analyses.
Conditions Studied
Interventions
- DRUG NSAID capsules
- DRUG Opioid capsule
Study Locations (2)
California
- Stanford Health Care - Redwood City
Utah
- University of Utah Health Care - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 121 participants |
| Start Date | 2021-12-27 |
| Est. Completion | 2027-08 |
| Phase | Phase 2 |
What NCT04676802 shows while recruiting
NCT04676802 is an interventional study that assigns participants to a tested intervention. The registered 121 participants enrollment target is mid-sized for trials with a published cap, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (56% lower).
The record links to 2 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 2 interventions - of which NSAID capsules is the first listed.
NCT04676802 reports a single indexed study location in California, Utah.
Frequently Asked Questions
What is clinical trial NCT04676802 about?
NCT04676802 is a clinical study titled "Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone". In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce ...
What is the current status of trial NCT04676802?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 121 participants. The study started on 2021-12-27. Estimated completion is 2027-08.
What conditions does trial NCT04676802 study?
This clinical trial studies the following conditions: Pain, Postoperative, Osteoarthritis Thumb.
What interventions are being tested in trial NCT04676802?
The interventions under investigation include: NSAID capsules (DRUG), Opioid capsule (DRUG).
Who is sponsoring clinical trial NCT04676802?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04676802 being conducted?
This trial has 2 study locations across California, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Postoperative
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04676802's enrollment target sits among peer trials
121 34th of 113 higher than 80 of 113 other Pain, Postoperative trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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