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NCT05604131 · ClinicalTrials.gov registry record · Phase 2

Cardiac MRI-guided Deferiprone Therapy for Acute Myocardial Infarction Patients

A Phase 2 study of Acute Myocardial Infarction Type 1, sponsored by Rohan Dharmakumar.

Recruiting
Registry status
Phase 2
Development phase
89
Enrollment target
1
Study location

NCT05604131: Recruiting Phase 2 study of Acute Myocardial Infarction Type 1, sponsored by Rohan Dharmakumar.

NCT05604131 is a Phase 2 study of Acute Myocardial Infarction Type 1 that is actively recruiting participants, run by Rohan Dharmakumar. The registered enrollment target is 89 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (33% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05604131, a Phase 2 study of Acute Myocardial Infarction Type 1, is actively recruiting participants, sponsored by Rohan Dharmakumar.

RECRUITING
Registry status
Phase 2
Development phase
89 participants
Enrollment target
1
Study location

Study Summary

The objective of this randomized, controlled pilot study is to determine the efficacy of Deferiprone to reduce the amount of free iron inside the hemorrhagic zone of myocardial infarction among hemorrhagic myocardial infarction patients.

Primary Outcome

Percentage reduction of hemorrhagic zone iron content by cardiac magnetic resonance at 6 months relative to baseline

Interventions

  • DRUG Placebo
  • DRUG Deferiprone Tablets

Study Locations (1)

Indiana

  • IU Methodist Hospital (IUHealth) - Indianapolis

Trial Details

FieldValue
Enrollment Target 89 participants
Start Date 2022-11-08
Est. Completion 2029-08-31
Phase Phase 2
Rohan Dharmakumar

8 total trials

What NCT05604131 shows while recruiting

NCT05604131 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 89 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (33% lower).

The record links to 1 condition, with Acute Myocardial Infarction Type 1 appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05604131 reports a single indexed study location in Indiana.

Frequently Asked Questions

What is clinical trial NCT05604131 about?

NCT05604131 is a clinical study titled "Cardiac MRI-guided Deferiprone Therapy for Acute Myocardial Infarction Patients". The objective of this randomized, controlled pilot study is to determine the efficacy of Deferiprone to reduce the amount of free iron inside the hemorrhagic zone of myocardial infarction among hemorrhagic myocardial infarction patients.

What is the current status of trial NCT05604131?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 89 participants. The study started on 2022-11-08. Estimated completion is 2029-08-31.

What conditions does trial NCT05604131 study?

This clinical trial studies the following conditions: Acute Myocardial Infarction Type 1.

What interventions are being tested in trial NCT05604131?

The interventions under investigation include: Placebo (DRUG), Deferiprone Tablets (DRUG).

Who is sponsoring clinical trial NCT05604131?

This trial is sponsored by Rohan Dharmakumar, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05604131 being conducted?

This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT05604131's enrollment target sits among peer trials

89 802nd of 2000 higher than 1,198 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05604131, the US trial registry maintained by the National Library of Medicine. NCT05604131 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.