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NCT02098434 · ClinicalTrials.gov registry record · NA
Ovarian Hormones and Stress Induced Drug Craving
A NA study of Cocaine Dependence, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- NA
- Development phase
- 29
- Enrollment target
- 1
- Study location
NCT02098434: Completed NA study of Cocaine Dependence, sponsored by Medical University of South Carolina.
NCT02098434 is a NA study of Cocaine Dependence that has completed, run by Medical University of South Carolina. The registered enrollment target is 29 participants, below the 298-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02098434, a NA study of Cocaine Dependence, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- NA
- Development phase
- 29 participants
- Enrollment target
- 1
- Study location
Study Summary
The study is investigating the impact of progesterone and estrogen on brain areas that are involved with stress response and drug craving. The study will involve 40 women who will participate in the Montreal Imaging Stress Task (MIST) while undergoing fMRI scanning procedures. Half of the women will complete the procedures during the luteal phase of the menstrual cycle; the other half will complete procedures during the follicular phase. Subjective and physiological measures (cortisol levels) will be used to measure stress and craving response. Hypothesis 1A is that all women will exhibit increased craving, stress response, salivary cortisol and BNST and limbic nuclei activation in response to the MIST task. Hypothesis 1B is that these increased responses will be higher for women in the luteal phase than for women in the follicular phase of the menstrual cycle.
Primary Outcome
Exposure to the MIST task will increase activation in these brain areas as measured by fMRI scanning procedures, and the increase will be more pronounced for women in the luteal rather than follicular phase of the menstrual cycle.
Conditions Studied
Interventions
- BEHAVIORAL Montreal Imaging Stress Task
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2010-10 |
| Est. Completion | 2013-07 |
| Phase | NA |
What the finished NCT02098434 record still lists
NCT02098434 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 298-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Cocaine Dependence appearing as the primary indexed condition, and to 1 intervention - of which Montreal Imaging Stress Task is the first listed.
NCT02098434 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT02098434 about?
NCT02098434 is a clinical study titled "Ovarian Hormones and Stress Induced Drug Craving". The study is investigating the impact of progesterone and estrogen on brain areas that are involved with stress response and drug craving. The study will involve 40 women who will participate in the Montreal Imaging Stress Task (MIST) while undergoing fMRI scanning procedures. Half of the women will...
What is the current status of trial NCT02098434?
This trial is currently completed. It is a NA study. The enrollment target is 29 participants. The study started on 2010-10. Estimated completion is 2013-07.
What conditions does trial NCT02098434 study?
This clinical trial studies the following conditions: Cocaine Dependence.
What interventions are being tested in trial NCT02098434?
The interventions under investigation include: Montreal Imaging Stress Task (BEHAVIORAL).
Who is sponsoring clinical trial NCT02098434?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02098434 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cocaine Dependence
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02098434's enrollment target sits among peer trials
29 32nd of 38 higher than 7 of 38 other Cocaine Dependence trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cocaine Dependence trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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