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NCT06504589 · ClinicalTrials.gov registry record
A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators
A clinical trial of Cystic Fibrosis, sponsored by Nicole Hamblett.
- Recruiting
- Registry status
- 400
- Enrollment target
- 20
- Study locations
NCT06504589: Recruiting study of Cystic Fibrosis, sponsored by Nicole Hamblett.
NCT06504589 is a study of Cystic Fibrosis that is actively recruiting participants, run by Nicole Hamblett. The registered enrollment target is 400 participants, above the 177-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (126% higher). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06504589, a study of Cystic Fibrosis, is actively recruiting participants, sponsored by Nicole Hamblett.
- RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 20
- Study locations
Study Summary
The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not take CFTR modulators. This data may be used to inform CF research, help design CF clinical trials and support the development of new treatments for people with CF who do not take CFTR modulators. Another goal of this study is to learn about research involvement for people with CF who do not take CFTR modulators, engage them in research, and give them an opportunity to learn about what is involved in participating in a CF research study.
Primary Outcome
Mean change (standard deviation) in percent predicted forced expiratory volume in 1 second (ppFEV1) as measured by in-clinic spirometry from baseline to 12 months post-baseline.
Conditions Studied
Study Locations (20)
California
- University of California San Diego - La Jolla
- Childrens Hospital Los Angeles - Los Angeles
- Stanford University Medical Center - Palo Alto
- University of California, San Francisco - Adult Center - San Francisco
- University of California, San Francisco - Peds Center - San Francisco
Florida
- University of Florida - Gainesville
- University of Miami - Miami
- Central Florida Pulmonary Group - Orlando
- Tampa General Hospital - Tampa
Arizona
- Phoenix Children's Hospital - Phoenix
- Tucson Cystic Fibrosis Center - Tucson
Colorado
- Children's Hospital Colorado - Aurora
- National Jewish Health - Denver
Georgia
- Children's Healthcare of Atlanta and Emory University - Atlanta
- Augusta University - Augusta
Alabama
- The Children's Hospital Alabama, University of Alabama at Birmingham - Birmingham
Arkansas
- University of Arkansas for Medical Sciences - Little Rock
Idaho
- Saint Luke's Cystic Fibrosis Center of Idaho - Boise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2024-09-18 |
| Est. Completion | 2029-08-14 |
What NCT06504589 shows while recruiting
NCT06504589 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, above the 177-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (126% higher).
The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 0 interventions.
NCT06504589 names 20 study sites across 10 states, led by California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT06504589 about?
NCT06504589 is a clinical study titled "A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators". The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not take CFTR modulators. This data may be used to inf...
What is the current status of trial NCT06504589?
This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2024-09-18. Estimated completion is 2029-08-14.
What conditions does trial NCT06504589 study?
This clinical trial studies the following conditions: Cystic Fibrosis.
Who is sponsoring clinical trial NCT06504589?
This trial is sponsored by Nicole Hamblett, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06504589 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cystic Fibrosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06504589's enrollment target sits among peer trials
400 16th of 169 higher than 153 of 169 other Cystic Fibrosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cystic Fibrosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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