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NCT00924768 · ClinicalTrials.gov registry record · Phase 1
A Study of Inhalation of 20,000 EU CCRE and Mucociliary Clearance (MCC) in Otherwise Healthy Individuals Who Are Current Cigarette Smokers
A Phase 1 study of Healthy and Cigarette Smoking, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT00924768: Completed Phase 1 study of Healthy and Cigarette Smoking, sponsored by University of North Carolina, Chapel Hill.
NCT00924768 is a Phase 1 study of Healthy and Cigarette Smoking that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 12 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00924768, a Phase 1 study of Healthy and Cigarette Smoking, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this Phase 1 research study is to identify a dose of inhaled endotoxin that is safe (does not cause prolonged cough, shortness of breath or other problems), but causes changes in sputum cell samples that the scientists can measure. The investigators are also interested in seeing if the exposure to the endotoxin decreases the body's natural ability to clear mucus from the lungs.
Conditions Studied
Interventions
- BIOLOGICAL 20K EU CCRE
Study Locations (1)
North Carolina
- UNC Center for Environmental Medicine, Asthma and Lung Biology - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2009-05 |
| Est. Completion | 2012-06 |
| Phase | Phase 1 |
What the finished NCT00924768 record still lists
NCT00924768 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which 20K EU CCRE is the first listed.
NCT00924768 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT00924768 about?
NCT00924768 is a clinical study titled "A Study of Inhalation of 20,000 EU CCRE and Mucociliary Clearance (MCC) in Otherwise Healthy Individuals Who Are Current Cigarette Smokers". The purpose of this Phase 1 research study is to identify a dose of inhaled endotoxin that is safe (does not cause prolonged cough, shortness of breath or other problems), but causes changes in sputum cell samples that the scientists can measure. The investigators are also interested in seeing if th...
What is the current status of trial NCT00924768?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2009-05. Estimated completion is 2012-06.
What conditions does trial NCT00924768 study?
This clinical trial studies the following conditions: Healthy, Cigarette Smoking.
What interventions are being tested in trial NCT00924768?
The interventions under investigation include: 20K EU CCRE (BIOLOGICAL).
Who is sponsoring clinical trial NCT00924768?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00924768 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00924768's enrollment target sits among peer trials
12 996th of 1090 higher than 61 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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