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Necrotizing Enterocolitis clinical trials
3 of 15 indexed Necrotizing Enterocolitis trials are currently recruiting.
15 US clinical trials · 3 currently recruiting
Necrotizing Enterocolitis is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Infant Bacterial Therapeutics, running 2 of these trials.
The research picture
Necrotizing Enterocolitis has 15 registered US clinical trials, 3 of them open to new participants right now, about 20% of the total.
- 3
- recruiting participants now
- 20%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Infant Bacterial Therapeutics
Active & Recent Trials
15 total, page 1 of 1
Early Predictors of Necrotizing Enterocolitis in Neonates
Nationwide Children's Hospital
NCT03210831
Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants
Crouse Hospital
NCT04284280
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis
Noveome Biotherapeutics, formerly Stemnion
NCT06315738
IBP-9414 for the Prevention of Necrotizing Enterocolitis - The Connection Study
Infant Bacterial Therapeutics
NCT03978000
RBC Irradiation, Anemia and Gut Injury
Emory University
NCT02741648
A Cohort Study of the Intestinal Microbiota of Premature Infants
University of California, Davis
NCT03717584
RIC-NEC Randomized Controlled Trial
The Hospital for Sick Children
NCT05279664
Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus
University of California, San Francisco
NCT01958320
Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections
The Emmes Company
NCT00621192
Comparison of Two Surgical Treatments for Necrotizing Enterocolitis in Human Infants
Yale University
NCT00252681
IBP-9414 for the Prevention of Necrotizing Enterocolitis
Infant Bacterial Therapeutics
NCT02472769
Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus
University of Utah
NCT03551600
Splanchnic Tissue Oxygenation During Enteral Feedings in Anemic Premature Infants at Risk for Necrotizing Enterocolitis
University of Utah
NCT01735578
Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy
Wake Forest University
NCT01306838
Collaborative Research Group for Necrotizing Enterocolitis
Washington University School of Medicine
NCT00828451
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 3 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Necrotizing Enterocolitis Trial Landscape
15 indexed Necrotizing Enterocolitis studies · 3 recruiting (20%).
Phase mix: 1 late (III/IV) vs 6 early (I/II).
Top sponsor: Infant Bacterial Therapeutics (2 trials), 9 others listed. 15 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Necrotizing Enterocolitis?
PlainTrial tracks 15 US clinical trials for Necrotizing Enterocolitis, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Necrotizing Enterocolitis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.