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NCT00739453 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Dose-escalation Study of OSI-906 and Erlotinib (Tarceva®)

A Phase 1 study of Advanced Solid Tumors, sponsored by Astellas Pharma.

Completed
Registry status
Phase 1
Development phase
95
Enrollment target
4
Study locations

NCT00739453 is a Phase 1 study of Advanced Solid Tumors that has completed, run by Astellas Pharma. The registered enrollment target is 95 participants, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (52% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT00739453, a Phase 1 study of Advanced Solid Tumors, has completed, sponsored by Astellas Pharma.

COMPLETED
Registry status
Phase 1
Development phase
95 participants
Enrollment target
4
Study locations

Study Summary

Multicenter, open-label, phase 1, cohort dose escalation study to determine the Maximum Tolerated Dose (MTD) of OSI-906 in combination with erlotinib

Conditions Studied

Advanced Solid Tumors

Interventions

  • DRUG erlotinib
  • DRUG OSI-906

Study Locations (4)

Colorado

  • University of Colorado Health Science Center - Aurora

Maryland

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center - Baltimore

Michigan

  • Hudson-Webber Cancer Research Center, Karmanos Cancer Institute - Detroit

Other

  • University of Oxford Department of Medical Oncology - Oxford

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2008-10-23
Est. Completion 2012-03-03
Phase Phase 1

Sponsor

Astellas Pharma

165 total trials

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What the Registry Record Tells You About NCT00739453

The ClinicalTrials.gov registry entry for NCT00739453 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 95 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (52% lower). The listed sponsor is Astellas Pharma, which has 165 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 2 interventions - of which erlotinib is the first listed.

NCT00739453 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Colorado, Maryland, Michigan.

Frequently Asked Questions

What is clinical trial NCT00739453 about?

NCT00739453 is a clinical study titled "A Phase 1 Dose-escalation Study of OSI-906 and Erlotinib (Tarceva®)". Multicenter, open-label, phase 1, cohort dose escalation study to determine the Maximum Tolerated Dose (MTD) of OSI-906 in combination with erlotinib

What is the current status of trial NCT00739453?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 95 participants. The study started on 2008-10-23. Estimated completion is 2012-03-03.

What conditions does trial NCT00739453 study?

This clinical trial studies the following conditions: Advanced Solid Tumors.

What interventions are being tested in trial NCT00739453?

The interventions under investigation include: erlotinib (DRUG), OSI-906 (DRUG).

Who is sponsoring clinical trial NCT00739453?

This trial is sponsored by Astellas Pharma, which has 165 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00739453 being conducted?

This trial has 4 study locations across Colorado, Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.